Practice guidelines for managing dyspepsia and active H. pylori infection have been issued by the American Gastroenterological Association and the American College of Gastroenterology. Both guidelines endorse the test-and-treat protocol for uninvestigated patients 55 years of age or younger.

American Gastroenterological Association Medical Position Statement: Evaluation of Dyspepsia

American College of Gastroenterology Guidelines on the Management of Helicobacter pylori Infection

American Family Physician Guidelines

American College of Cardiology Foundation(ACCF)/ACG/AHA 2008 Expert Consensus Document on Reducing the Gastrointestinal Risks of Antiplatelet Therapy and NSAID Use: A report of the American College of Cardiology Foundation Task Force on Clinical Expert Consensus Documents