Product Filters
TPO Products (5)
| 姓名 | 种类 | 形式 | 宿主/来源 | 亚型 | 主要应用 | 单位 | 安全信息表 | COA | 点击此处订购样品 | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Human Tpo, Recombinant | Aff.Pur. | Baculovirus | N/A | EIA,WB | MG | A01309H | View SDS | View COA | Order A Sample | |||
| MAb to Thyroid Peroxidase | Monoclonal | Purified | Mouse | IgG1 | EIA,LF,WB | MG | E86415M | View SDS | View COA | Order A Sample | ||
| MAb to Thyroid Peroxidase | Monoclonal | Purified | Mouse | IgG1 | EIA,Pr,WB | MG | E01311M | View SDS | View COA | Order A Sample | ||
| MAb to Thyroid Peroxidase | Monoclonal | Purified | Mouse | IgG1 | EIA,Pr,WB | MG | E01310M | View SDS | View COA | Order A Sample | ||
| MAb to Thyroid Peroxidase | Monoclonal | Purified | Mouse | IgG1 | EIA,Pr | MG | E01309M | View SDS | View COA | Order A Sample |
甲状腺过氧化物酶 (TPO)
TPO作为一种酶，其作用是催化碘化物在甲状腺球蛋白酪氨酸残基上的氧化，合成三碘甲状腺原氨酸(T3)和甲状腺素(T4)。 TPO相关疾病通常与自身免疫相关，甲状腺过氧化物酶是产生抗甲状腺过氧化物酶抗体(anti-TPO抗体)的自身抗体的一个常见表位。 因此，抗TPO抗体可在桥本甲状腺炎和格雷夫氏病等大多数自身免疫性疾病中检测到，也可在恶性贫血、I型糖尿病或其他激活免疫系统的疾病等非甲状腺自身免疫性疾病患者中发现。
Diagnosis
The TPO antibody assay is the most sensitive test for autoimmune thyroid disease, and it is useful in differentiating thyroid autoimmune disorders from non-autoimmune goiter or hypothyroidism. It employs both non-competitive and competitive assay formats using TPO antigen. Traditionally, human native TPO purified from thyroid glands was used; however, studies have shown that the soluble extracellular domain of recombinant human thyroid peroxidase (rTPO) produced in insect cells has immunochemical properties similar to native human thyroid peroxidase (Haubruck et al. 1993).
与我们的专业团队联系
想了解更多迈迪安免疫和分子产品信息？欢迎与我们联系