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阻断剂和免疫球蛋白

Immunoassay blockers are used in diagnostic assays to reduce non-specific binding and other interference that can lead to false-positive results. Specifically, interference from human anti-mouse antibodies (HAMA), rheumatoid factor (RH), and heterophilic antibodies (HA) are a major concern in both paired monoclonal sandwich assays and competitive assays. Specialized blockers are required in these assays to reduce any interference and to ensure the assay's accuracy.

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迈迪安的阻断剂系列包括主动阻断剂,如TRU Block™, 和被动阻断剂,如小鼠IgG。其中TRU Block™ULTRA(新一代HAMA阻断剂)是经过多年研发目前市面上最强大的免疫分析干扰阻断剂。它可以在侧向引流和ELISA检测中全面抗HAMA, HA和RF的干扰。IVD制造商能够在较低浓度下使用这种主动阻断剂,并实现更高的检测性能。

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