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EGFR

表皮生长因子受体(EGFR)是一种酪氨酸激酶,通过结合其配体表皮生长因子(EGF)刺激增殖和分化。研究表明在许多实体肿瘤中存在EGFR的高表达或异常表达,例如头颈部、乳腺、肾脏、结肠、多形性胶质母细胞瘤和非小细胞肺癌。EGFR上调或突变的临床诊断对于确定哪些肿瘤对使用酪氨酸激酶抑制剂的癌症治疗有反应很重要。EGFR上调通常通过血清学检测进行诊断,EFGR突变通过qPCR或测序进行诊断。

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EGFR Products (4)

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姓名 种类 形式 宿主/来源 亚型 主要应用 单位   安全信息表 COA 点击此处订购样品
MAb to EGFR,activated pTyr1173 Monoclonal Purified Mouse IgG1,k EIA,IP,IB,ICC MG K67902M View SDS View COA Order A Sample
MAb to EGFR pS1047 Monoclonal Purified Mouse IgG1 EIA,ICC,IB,IP MG K67190M View SDS View COA Order A Sample
MAb to EGFR, pTyr 845 Monoclonal Purified Mouse IgG1 EIA,IP MG K67123M View SDS View COA Order A Sample
MAb to EGFR, pTyr 1045 Monoclonal Purified Mouse IgG1 EIA,IB,IP MG K67112M View SDS View COA Order A Sample

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