Molecular Reagents for SARS-CoV-2 Assays
Meridian’s portfolio of RT-qPCR master mixes have been designed to simplify the development of molecular assays and enable new features such as extraction-free amplification. Each master mix contains a hot-start polymerase, dNTPs, buffer, and other components optimized for each particular application (e.g. lyophilization). Only primers and probes are required to complete the assay formula.
By using a master mix in which the upstream formulation chemistry has already been refined for superior performance under fast or challenging cycling conditions, assay development can be concentrated to other elements of the assay design. Important features for successful next-generation molecular assays include earlier detection, simplified workflow format, and shorter time to results.
Meridian provides a comprehensive solution to each type of COVID-19 assay. Our range of optimized RT-qPCR mixes are ideal for fast and accurate molecular testing and include options for direct detection on clinical samples. For immunoassays, Meridian has several pairs of high-performing monoclonal antibodies to SARS-CoV-2 and a range of recombinant antigens including a panel of antigens that represent the different World Health Organization’s Variants of Concern. The nucleoprotein MAb pair (9547/9548) is currently used in several commercial rapid assays and is capable of detecting the major variant strains circulating globally (e.g. Alpha, Beta, Delta, Omicron).
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