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La (SS-B)

La (SS-B) is one of four autoantigens commonly referred to as extractable nuclear antigens (ENA). The other ENAs are SS-A/Ro, RNP, and Sm. Each ENA is composed of one or more proteins associated with small nuclear or cytoplasmic RNA species (snRNP) ranging in size from 80 to 350 nucleotides. Antibodies to ENA are common in patients with connective tissue diseases including lupus erythematosus (LE), mixed connective tissue disease, Sjogren syndrome, scleroderma, and polymyositis/dermatomyositis. Anti-La antibodies are found in 15-40% of Sjogren's patients and 10-10% of SLE patients and is testing for anti-La(SS-B) is useful for the differential diagnosis of SLE and Sjogren syndrome.

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Clear Results
5 Results
Name
Type
Format
Host/Source
Isotype
Tested Apps
Unit
Catalog
SDS
COA
Request Sample
SS-B (La) Recombinant
Antigen
Purified
Insect Cells
N/A
EIA
MG
R01691
Human anti SS-b antigen
Monoclonal
Purified
Human Donor
N/A
EIA
ML
K07104H
SS-b (La) antigen, Recombinant
Antigen
Purified
E. coli
N/A
EIA
MG
A01256H
SS-b (La) antigen
Antigen
Aff.Pur.
Bovine
N/A
EIA
UT
A41022H
SS-b (La) antigen
Antigen
Aff.Pur.
Bovine Thymus
N/A
EIA
MG
A3C022B

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