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AMH

Anti-Müllerian Hormone (AMH) is a glycoprotein hormone structurally related to inhibin and activin and is part of the transforming growth factor beta superfamily. AMH is considered an extremely sensitive marker of ovarian function and ovarian aging.

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AMH Products (16)

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Name Type Format Host/Source Isotype Tested Apps Unit Catalog Buffer Immunogen Recombinant Description Notes SDS COA New Product Recommended Product Order a Sample
AMH, Recombinant Antigen Aff.Pur. Cell Culture N/A EIA,WB,Pr BF 9604 No View SDS View COA 0 Order a Sample
MAb to AMH Monoclonal Purified, Liquid Cell Culture IgG1 EIA,LF,WB MG 9603 No View SDS View COA 0 Order a Sample
MAb to AMH Monoclonal Purified, Liquid Cell Culture IgG1 EIA,LF,WB MG 9602 No View SDS View COA 0 Order a Sample
AMH Recombinant Antigen Purified Human N/A EIA,WB BJ 9564 No View SDS View COA 0 Order a Sample
AMH Recombinant Antigen Purified Human N/A N/A BJ 9563 No View SDS View COA 0 Order a Sample
Anti-Mullerian Hormone Ab Polyclonal Aff.Pur. Chicken N/A EIA MG 8185 No View SDS View COA 0 Order a Sample
AMH Recombinant Antigen Purified E. coli N/A EIA,CLI,Pr MG R01713 No View SDS View COA 0 Order a Sample
AMH Recombinant Antigen Purified E. coli N/A EIA,WB,Pr,CLI,LF MG R01712 No View SDS View COA 0 Order a Sample
MAb to AMH Monoclonal Purified Mouse IgG3 EIA,LF,CLI,Pr MG E01355M No View SDS View COA 0 Order a Sample
MAb to AMH Monoclonal Purified Mouse IgG1 EIA,LF,CLI,Pr MG E01352M No View SDS View COA 0 Order a Sample
MAb to AMH Monoclonal Purified Mouse IgG2b EIA,CLI,LF,Pr MG E01353M No View SDS View COA 0 Order a Sample
MAb to AMH Monoclonal Purified Mouse IgG3 EIA,LF,CLI,Pr MG E01354M No View SDS View COA 0 Order a Sample
MAb to AMH Monoclonal Purified Mouse IgG1 EIA,LF,CLI,Pr MG E01348M No View SDS View COA 0 Order a Sample
MAb to AMH Monoclonal Purified Mouse IgG2b EIA,CLI,Pr MG E01349M No View SDS View COA 0 Order a Sample
MAb to AMH Monoclonal Purified Mouse IgG2a EIA,CLI,Pr MG E01350M No View SDS View COA 0 Order a Sample
MAb to AMH Monoclonal Purified Mouse IgG2a EIA,LF,Pr,CLI MG E01347M No View SDS View COA 0 Order a Sample

Anti-Müllerian Hormone (AMH)

AMH is expressed by granulosa cells of the ovary during a female’s reproductive years and plays a key role in growth differentiation and folliculogenesis. Specifically, AMH expression inhibits primordial follicle recruitment and decreases the sensitivity of follicles for the FSH-dependent selection. Besides its functional role in the ovary, AMH serum levels also serve as a biomarker for ovarian reserve. Overall, a higher level of AMH in normal, healthy women aged 30-44 has a positive correlation with natural fertility for spontaneous conception. AMH is also useful to assess conditions such as polycystic ovary syndrome and premature ovarian failure.

Diagnosis

AMH is a dimeric glycoprotein molecule that consists of two identical subunits linked by sulfide bridges. Each subunit contains a pro-region (pro-AMH or N-terminal) and a C-terminal domain (also called the “mature” region) which is cleaved at monobasic sites between the two domains. After cleavage, the pro-region (110-kDa) and C-terminal (25 kDa) homodimers remain associated in a noncovalent complex that bind to AMH Receptor II to activate signaling.

Diagnostic tests that measure AMH levels in serum or plasma are usually quantitative sandwich-ELISA that use antibodies directed against epitopes in the stable pro-region and mature region.

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