Lyme disease is caused by the bacteria Borrelia burgdorferi, which is transmitted to humans by a bite from an infected black-legged or deer tick. Untreated, Lyme disease can produce a wide range of symptoms that vary depending on the stage of infection but include fever, rash, facial paralysis, and arthritis.
Diagnosis relies on a two-step process, with initial screening for antibodies to B. burgdorferi by ELISA and confirmation by Western Blot. Lyme disease can also be diagnosed by testing a sample of a skin lesion by PCR.
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