Myoglobin (MYO) is the primary oxygen-carrying pigment of muscle tissue. It is present in high levels in serum when muscle tissue is damaged, such as after a heart attack. It is a non-specific marker, and in the absence of skeletal muscle trauma, it can be used as an early indicator of myocardial infarction and other cardiac markers such as CK-MB or cTnI. Myoglobin achieves its maximal diagnostic sensitivity within 5 hours of symptom onset and can be detected using a two-site sandwich immunoassay.
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