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Rubella Virus

Rubella, also known as German Measles, is a viral illness caused by a togavirus of the genus Rubivirus and is an infection that primarily affects the skin and lymph nodes. It is generally a mild disease in adults and children, but it can have devastating effects on infants.

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16 Results
Name
Type
Format
Host/Source
Isotype
Tested Apps
Unit
Catalog
SDS
COA
Request Sample
MAb to Rubella (clone #2-6)
Monoclonal
Purified
Mouse
-
Pr
MG
EV9525
MAb to Rubella (clone #2-42)
Monoclonal
Purified
Mouse
-
Pr
MG
EV9526
Goat anti-Rubella Virions
Polyclonal
HRP
Goat
N/A
ICC
ML
B65704P
Goat anti-Rubella Virus Virion
Polyclonal
FITC
Goat
N/A
IFA
ML
B65703F
Goat A' Rubella Virus Virions
Polyclonal
Purified
Goat
N/A
HI, IFA
ML
B65105G
Rubella RSVP antigen
Antigen, Other
Purified
Vero Cells
N/A
EIA, WB
MG
6200
Rubella Virus E2, Recomb.
Antigen, Other
Purified
E. coli
N/A
EIA, WB
MG
R18292
MAb to Rubella C Protein
Monoclonal
Purified
Mouse
IgG1,k
EIA, IFA, WB
MG
C66496M
MAb to Rubella (E1)
Monoclonal
Purified
Mouse
IgG2a
EIA, WB
MG
C66503M
Rubella Virus Capsid, Recomb.
Antigen, Other
Purified
E. coli
N/A
EIA, WB
MG
R18092
Rubella Virus E1 Mosaic Recomb
Antigen, Other
Purified
E. coli
N/A
EIA, WB
MG
R18192
MAb to Rubella (E1)
Monoclonal
Purified
Mouse
IgG2a
EIA, WB
MG
C86323M
Rubella Virus Grade IV Ag
Antigen, Other
Partially Purified
Vero Cells
N/A
CLIA, EIA, Pr, WB
MG
6076
Rubella Virus E1 Mosaic Recomb
Antigen, Other
Purified
E. coli
N/A
EIA, WB
MG
R01491
Rubella Virus Grade III Ag
Antigen, Other
Purified
Vero Cells
N/A
EIA, WB
ML
6075
Rubella Virus Grade IV PBS Ag
Antigen, Other
Purified
Vero Cells
N/A
CLIA, EIA, WB
MG
6123

Rubella Virus

The primary medical danger of rubella is the infection of pregnant women because it can cause congenital rubella syndrome (CRS) in a developing fetus. Since the introduction of the measles-mumps-rubella (MMR) vaccine, rubella is much less common, however, several countries still do not include this vaccine in their immunization schedule. In the absence of vaccination, rubella is an endemic disease with epidemics every 6 to 9 years. Rubella is spread by coughing and sneezing and the virus resides in the nose and throat of an infected person with an average incubation period of 14-21 days. A person infected with rubella may spread the disease to others beginning one week before the rash occurs. Symptoms generally occur 2-3 weeks after exposure to the virus and includes a mild fever, headache and runny nose.

CONGENITAL INFECTION

A rubella infection just before conception (0-28 days) or during the first trimester in pregnancy has the highest rate of transmission to the fetus (90%) resulting in congenital rubella syndrome (CRS). At 14 weeks, this incidence is reduced to 52%, and by the end of the second trimester, the incidence drops to 25%. Fetal rubella infection often results in spontaneous abortion or severe fetal defects, including heart, brain, ear or eye malformations, deafness, microcephaly and mental retardation. Before the introduction of the vaccine, up to 4 babies in every 1000 live births were born with CRS.

Diagnosis

Rubella virus can be detected from nasal, throat, urine and blood specimens from infected individuals. Diagnosis is usually made by the detection of rubella-specific IgM antibodies which are usually present 4–30 days after the onset of illness. However, reliable serodiagnosis requires the discrimination of specific IgM primary rubella from persistent, reactivated or non-specific IgM reactivity. Recent infection can be confirmed or excluded by additional assays such as rubella IgG avidity and immunoblot analysis.

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