Close

Scl-70

Scl-70 antigen is an abundant nuclear protein that is an extractable fragment (70 kD) of a larger protein (100-105kD), Topoisomerase I. Anti-Scl-70 antibodies are a serologic marker of diffuse cutaneous systemic sclerosis (dcSSc), a connective tissue disease characterized by microvascular damage and fibrosis of the skin and visceral organs. Autoantibodies to Scl-70 are also a specific serologic marker for systemic sclerosis and acrosclerosis, but are not usually present in other autoimmune rheumatic diseases unless some cutaneous symptoms of scleroderma are present.

Have questions about a product?

Contact us to learn more about Meridian’s molecular or immunoassay reagent portfolio. We want to hear from you!

Contact A Specialist
Product Filters

Clear All

Scl-70 Products (3)

Filters Close
Name Type Format Host/Source Isotype Tested Apps Unit Catalog SDS COA Request Sample
Scl-70 antigen Antigen Purified Bovine Thymus N/A EIA MG A3C301B View SDS View COA Order A Sample
Scl-70 antigen Antigen Aff.Pur. Rabbit Thymus N/A EIA UT A07322B View SDS View COA Order A Sample
Human anti Scl-70 antigen Monoclonal Purified Human Donor N/A EIA,ID ML K07105H View SDS View COA Order A Sample

Get In Touch With A Specialist

Have questions about a product? Want to learn more about Meridian’s molecular or immunoassay reagent portfolio? We want to hear from you!


By submitting your information in this form, you agree that your personal information may be stored and processed in any country where we have facilities or service providers, and by using our “Contact Us” page you agree to the transfer of information to countries outside of your country of residence, including to the United States, which may provide for different data protection rules than in your country. The information you submit will be governed by our Privacy Statement.

Learn More About Us

Learn More
Welcome to
logo blue

Please select your country to continue

Continue
CN