TRU Block™ is an immunoassay interference blocker that contains specific binders directed against all types of heterophilic interference including human anti-mouse antibodies (HAMA) and rheumatoid factor (RF) that can cause a false-negative or false-positive result. Once bound to the interfering antibodies, TRU Block™ prevents further binding of HA to other assay components through steric hindrance. Active blockers such as TRU Block™ can typically be used in lower concentrations than passive blocking reagents, which minimizes the reduction in assay signal commonly associated with passive blockers.
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