Canine parvovirus (CPV) is a highly contagious viral disease of dogs that commonly causes acute gastrointestinal illness in puppies and unvaccinated dogs. It is spread by dog-to-dog contact and contact with contaminated feces, environments, or people. The virus is resistant to heat, cold, humidity, and drying and can survive in the environment for long periods of time. Symptoms often associated with CPV include lethargy, depression, loss or lack of appetite, followed by a sudden onset of high fever, vomiting, and diarrhea. The most common method of testing for the presence of CPV is the fecal antigen ELISA test that detects CPV-specific antibodies followed by PCR.