Pioneering Sustainable Innovation in Immuno & Molecular Dx Reagents
At Meridian, we believe sustainability starts with us. Throughout our entire organization, we are committed to integrating sustainability principles and ethical practices into our business model. Our goal is to provide innovative, eco-conscious and cost-effective products to our customers, empowering them with solutions to increase global access to their tests, reduce waste, and enhance efficiency in their supply chains and assay workflows as they progress toward their sustainability goals.
Environmental sustainability is often described as a hierarchy of waste reduction: avoid, reduce, re‐use, and recycle. However for pathology testing, the opportunities for re‐using or recycling items are limited due to infection control. The main opportunities for reducing waste and CO2 emissions involve utilizing sustainable materials, optimizing supply chain logistics, reducing reagent volumes, and employing workflow efficiencies.
Meridian offers leading innovative and environmentally conscious products that can help you become more operationally efficient and sustainable.
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First-time Right Process Development
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Precision Plasmid Manufacturing
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High Throughput GMP Manufacturing
Process Development
Ensure first-time right manufacturing and 2-month faster tech transfer to GMP
When a process scales, variability can affect a delicate vector. Process development efforts including characterization and stability studies are critical for successful manufacturing at later clinical and commercial scale. CBM’s first-time right process development is underpinned by a Pilot Plant that can manufacture in GMP conditions with flexibility in scale and scheduling. Tech transfers are facilitated by having GMP teams train, develop documentation, and begin the bill of material for GMP manufacturing.
Precision Plasmid Manufacturing
Seamless supply chain eliminates 12-month waits
Plasmids are a critical starting material for vector production. As a common bottleneck, ensuring a steady supply is critical to uninterrupted manufacturing. CBM’s Precision PlasmidsTM guarantees quantity and quality (e.g., plasmid supercoiled topology of 80%+, absorbance ratio purity between 1.8 and 2.0) to support later vector yields.
High Throughput GMP Manufacturing
Up to 88% more batches annually per suite with capabilities for a wide array of viral vectors
Facilities were designed by former regulators to meet both clinical and commercial quality standards. There is no changeover required between clinical and commercial supply, further accelerating speed to market. Modular unit operations in downstream and upstream processes are decoupled to maximize efficiency and continuous manufacturing enabling 2 to 5X more batches per suite annually. The inaugural facility is engineered, built, and outfitted to support adeno-associated virus (AAV), lentivirus, adenovirus, retrovirus, herpes simplex virus, baculovirus, and other novel vectors safely and with the highest regulatory and segregation controls.
and expertise for creating your breakthrough medicine.
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Process Development
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Analytical Development and Testing
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Plasmid DNA Manufacturing
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Viral Vector Manufacturing
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Cell Therapy Manufacturing
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