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Hepatitis A (HAV)

Hepatitis A (HAV) is a contagious disease, spread by contact with infected people, their fluids and waste. It causes an acute infection of the liver that generally does not require treatment and can self-resolve. Young children infected with HAV typically have a milder form of the disease compared to adults who can be at risk of acute liver failure, especially if there is underlying chronic liver disease. HAV can affect people of all ages but can be prevented with vaccination.

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12 Results
Name
Type
Format
Host/Source
Isotype
Tested Apps
Unit
Catalog
SDS
COA
Request Sample
MAb to Hepatitis A Virus
Monoclonal
Purified
Mouse
IgG1
EIA, IFA
MG
C01853M
MAb to Hepatitis A Virus
Monoclonal
Purified
Mouse
IgG2a
EIA, IFA
MG
C01855M
MAb to Hepatitis A Virus
Monoclonal
Purified
Mouse
IgG2b
EIA, IFA
MG
C01854M
MAb Hepatitis A Virus (HAV)
Monoclonal
Purified
Mouse
IgG2a
EIA
MG
C65885M
MAb to Hepatitis A Virus
Monoclonal
Purified
Mouse
IgG1
EIA, IFA, IHC
MG
C65881M
Goat A' Hepatitis A Strn HM175
Polyclonal
Purified
Goat
N/A
EIA
ML
B65808G
HAV Vp3 Recomb.
Antigen, Other
Purified
E. coli
N/A
EIA, WB
MG
R18610
HAV VP1-P2A Recomb.
Antigen, Other
Purified
E. coli
N/A
EIA, WB
MG
R18810
HAV P2c-p3a Recomb.
Antigen, Other
Purified
E. coli
N/A
EIA, WB
MG
R18210
HAV VP1 Recombinant
Antigen, Other
Purified
E. coli
N/A
EIA, WB
MG
R18710
HAV Grade Ii Concentrate
Antigen, Other
Purified
FRhK-4 Cells
N/A
CLIA, EIA, WB
ML
8505
Hepatitis A antigen
Antigen, Other
Purified
FRhK-4 Cells
N/A
CLIA, EIA, WB
ML
8198

Hepatitis A (HAV)

Symptomatic HAV infections affect about 1.4 million people globally per year and the CDC estimates that 10% to 15% of people with HAV will have symptoms that persist or reoccur over a 6- to 9-month period. The virus is highly contagious and primarily transmitted by the fecal-oral route, by either person-to-person contact or through consumption of contaminated food or water. Currently, the most commonly identified risk factor among reported cases of acute HAV infection is contact with an infected household member or sexual partner. Antibodies produced in response to Hepatitis A last for life and protect against reinfection, although the best way to prevent Hepatitis A is by getting vaccinated.

Diagnosis

Hepatitis A cannot be distinguished from other types of viral hepatitis on the basis of clinical symptoms alone. For this reason, serologic tests that identify the presence of antibodies to HAV is the primary method for diagnosis. HAV specific anti-IgM indicates an acute infection and is detectable from 1-2 weeks after initial infection and persists for up to 14 weeks. A positive IgG result signifies that the acute stage of the illness past and the person is immune to further infection. IgG antibody to HAV is also found in the blood following vaccination. HAV has several critical immunogenic epitopes which require precise folding and to-date, recombinant techniques have not been able to mimic the conformation of these epitopes. As a result, most commercial HAV immunoassays use native HAV antigen as opposed to recombinant HAV proteins for antibody detection.

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