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Enterovirus

Enterovirus infections are caused by many different viruses including coxsackievirus, echovirus, enterovirus, and poliovirus. They are responsible for causing illnesses in 10 to 30 million people each year in the United States, primarily in the summer and fall and they are most common among children. Infections are highly contagious and typically affect many people in a community, sometimes reaching epidemic proportions.

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Enterovirus Products (32)

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Name Type Format Host/Source Isotype Tested Apps Unit Catalog Buffer Immunogen Recombinant Description Notes SDS COA New Product Recommended Product Order a Sample
Salmonella Typhimurium Antigen Lysate Cell Culture N/A LF,CON,ST ML A01716N No View SDS View COA 0 Order a Sample
Salmonella Enteritidis Antigen Lysate Cell Culture N/A LF,CON ML A01702N No View SDS View COA 0 Order a Sample
Salmonella Paratyphi B Antigen Lysate Cell Culture N/A LF,CON ML A01701N No View SDS View COA 0 Order a Sample
Salmonella Paratyphi A Antigen Lysate Cell Culture N/A LF,CON ML A01700N No View SDS View COA 0 Order a Sample
Salmonella typhi Antigen Lysate Cell Culture N/A LF,CON ML A01699N No View SDS View COA 0 Order a Sample
Enterovirus D EV70 Recomb Antigen Purified E. coli N/A LF,IM MG R01765 No View COA 0 Order a Sample
Enterovirus A EV71 Recomb Antigen Purified E. coli N/A LF,IM MG R01764 No View COA 0 Order a Sample
Enterovirus A Cox A16 Recomb Antigen Purified E. coli N/A LF,IM MG R01763 No View COA 0 Order a Sample
Salmonella Typhi Flag. Recomb Antigen Purified E. coli N/A EIA MG R01746 No View COA 0 Order a Sample
Enterovirus B Cox B3 Recomb Antigen Purified E. coli N/A LF,IM,ST MG R01737 No View COA 0 Order a Sample
Enterovirus C. Cox A24 Recomb Antigen Purified E. coli N/A LAT,IM,ST MG R01736 No View COA 0 Order a Sample
Enterovirus B Echo 18 Recomb Antigen Purified E. coli N/A LF,IM,ST MG R01735 No View COA 0 Order a Sample
Salmonella Typhi H Ag, Recomb. Antigen Purified E. coli N/A LF MG R01699 No View SDS View COA 0 Order a Sample
Salmonella typhi OMP, Recomb. Antigen Purified E. coli N/A EIA,WB MG R01670 No View SDS View COA 0 Order a Sample
Salmonella Typhi Pagc Recomb. Antigen Purified E. coli N/A N/A MG R01569 No View SDS View COA 0 Order a Sample
MAb to Salmonella Typhimurium Monoclonal Purified Mouse IgG1 EIA MG C86309M No View SDS View COA 0 Order a Sample
MAb to Salmonella (abd Groups) Monoclonal Purified Mouse IgG1 DB,EIA,IFA MG C86109M No View SDS View COA 0 Order a Sample
MAb to Salmonella Species Monoclonal Purified Mouse IgG2b EIA,IFA MG C65958M No View COA 0 Order a Sample
MAb to Salmonella Species Monoclonal Purified Mouse IgG2b EIA,IFA,ST MG C65957M No View SDS View COA 0 Order a Sample
MAb to Salmonella (ABCDE Grps) Monoclonal Purified Mouse IgG1 EIA,IFA,DB MG C65635M No View COA 0 Order a Sample
MAb to Salmonella Paratyphi A Monoclonal Purified Mouse IgG3 EIA,IFA,ST MG C01884M No View SDS View COA 0 Order a Sample
MAb to Enterovirus Monoclonal Purified Mouse IgG2a EIA,IFA MG C01700M No View SDS View COA 0 Order a Sample
MAb to Enterovirus 70 Monoclonal Purified Mouse IgG3 EIA,IFA MG C01670M No View SDS View COA 0 Order a Sample
MAb to Salmonella Typhi Monoclonal Purified Mouse IgG2a EIA,IFA,ST,Pr,LF MG C01362M No View SDS View COA 0 Order a Sample
MAb to Salmonella Species Monoclonal Purified Mouse IgG2b EIA,IFA,Pr MG C01361M No View SDS View COA 0 Order a Sample
MAb to Salmonella Species Monoclonal Purified Mouse IgG3 EIA,IFA,Pr,ST MG C01360M No View COA 0 Order a Sample
MAb to Salmonella Species Monoclonal Purified Mouse IgG2a EIA,IFA,Pr MG C01359M No View COA 0 Order a Sample
MAb to Salmonella Species Monoclonal Purified Mouse IgG2a EIA,Pr,IFA MG C01358M No View COA 0 Order a Sample
Rabbit anti Salmonella Sp. Polyclonal Biotin Rabbit N/A EIA,IFA ML B65707R No View COA 0 Order a Sample
Rabbit anti Salmonella Sp. Polyclonal HRP Rabbit N/A EIA,IHC ML B65704R No View COA 0 Order a Sample
Rabbit anti Salmonella Sp. Polyclonal FITC Rabbit N/A IFA ML B65703R No View COA 0 Order a Sample
Rabbit anti Salmonella Sp. Polyclonal Purified Rabbit N/A EIA,IFA ML B65701R No View SDS View COA 0 Order a Sample

Enterovirus

Enteroviruses infect an estimated 50 million people each year in the US and possibly a billion or more worldwide. Approximately 75% of enterovirus infections occur in children under 15 years of age, and the occurrence rates are highest in children under 1 year of age. Transmission occurs orally, either via aerosol or ingestion of contaminated food. Approximately 50-80% of enterovirus infections are mild or asymptomatic; however, they can also develop into severe and life-threatening diseases. Serologic studies have distinguished over 70 human enterovirus serotypes associated with 26 different syndromes and diseases, including coronary heart disease, type 1 diabetes, hand-foot-and-mouth disease, polio, and meningitis. Traditionally, enteroviruses were classified into four separate species: coxsackie, echovirus, enterovirus, and poliovirus. However, due to large overlaps in their epidemiologic and clinical characteristics, their taxonomy has changed, and newly identified viruses are now numbered, starting with EV68. To date, the following enterovirus subtypes have been identified:

Subtype Diseases

Poliovirus 1-3 Paralysis, aseptic meningitis, encephalitis, poliomyelitis

Coxsackie A1-A24 Herpangina, hand-foot-mouth, common cold

Coxsackie B1-B6 Pleurodynia, aseptic meningitis, encephalitis, pericarditis, myocarditis

Echovirus 1-9, 11-31 Paralysis, aseptic meningitis, encephalitis

Numbered Enteroviruses Herpangina, hand-foot-and-mouth, conjunctivitis (EV70), aseptic meningitis (eg. EV71)

Enterovirus outbreaks are common in the summer and fall, though they can cause infections year-round in tropical parts of the world. Several serotypes have been responsible for large outbreaks including:

  • Enterovirus 71: large outbreaks of Hand-Foot-and-Mouth Disease (HFMD) worldwide, especially in children in Asia
  • Echovirus 13, 18, and 30: several outbreaks of viral meningitis in the United States
  • Enterovirus D68: infected children in 49 states in 2014 and hospitalized them with severe respiratory illness
  • Coxsackievirus A16 & A6: the most common cause of HFMD in the United States
  • Coxsackievirus A24 & Enterovirus 70: seasonal worldwide outbreaks of acute hemorrhagic conjunctivitis since the 1970’s
  • Poliovirus: killed over 500,000 people worldwide each year in the 1940’s and 50’s. Vaccines are now available

Diagnosis

Diagnostic methods for enterovirus include virus isolation, nucleic acid testing (NAT), and serological tests such as ELISA, complement fixation (CF), and neutralization assays. In particular, IgM ELISAS have proven very useful in cases of meningitis when cerebral spinal fluid samples are not available. Also, the rapid serotype identification of enterovirus is important in differentiating non-poliovirus enterovirus pathogens from vaccine strain polioviruses that can be shed for some time after vaccination, especially in age groups in which oral poliovirus vaccines are usually administered.

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