Prolactin

Prolactin (PRL) is a hormone that is best known for its role in initiating and maintaining lactation in mammals. It is secreted by the anterior pituitary gland and controlled by the hypothalamus.

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Prolactin Products (8)

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Name Type Format Host/Source Isotype Tested Apps Unit Catalog SDS COA Request Sample
Human Prolactin Recombinant Antigen Purified E. coli N/A CLI MG A01467H View SDS View COA Order A Sample
MAb to Prolactin Monoclonal Purified Mouse IgG2a,k EIA,Pr MG MAF10-710 View SDS View COA Order A Sample
MAb to Prolactin Monoclonal Purified Mouse IgG1,k EIA,Pr MG MAF10-245 View SDS View COA Order A Sample
MAb to Prolactin Monoclonal Purified Mouse IgG2a,k EIA,Pr MG MAF10-216 View SDS View COA Order A Sample
MAb to Prolactin Monoclonal Purified Mouse IgG1,k EIA,Pr MG MAF10-145 View SDS View COA Order A Sample
MAb to Prolactin Monoclonal Purified Mouse IgG1,k EIA,Pr MG MAF10-111 View SDS View COA Order A Sample
MAb to Human Prolactin Monoclonal Purified Mouse IgG1,k Pr,EIA MG E20630M View SDS View COA Order A Sample
MAb to Human Prolactin Monoclonal Purified Mouse IgG1,k Pr,EIA MG E20122M View SDS View COA Order A Sample

Diagnosis

The biologically active form of prolactin is the 23-kDa monomeric polypeptide secreted by the pituitary gland; however, circulating prolactin exists in a number of additional forms. Big prolactin (60 kDa) and macroprolactin (150 kDa), which are present in serum in varying quantities, can cause apparent hyperprolactinemia, but they have no clinical importance because they exhibit little biological activity. Several studies have shown that prolactin two-site sandwich immunoassays are susceptible to interference from macroprolactin. Current best practice recommends that all sera with increased total prolactin concentrations be subfractionated by PEG precipitation to measure the bioactive monomeric prolactin concentration, a more clinically meaningful variable.

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