Prolactin
Prolactin (PRL) is a hormone that is best known for its role in initiating and maintaining lactation in mammals. It is secreted by the anterior pituitary gland and controlled by the hypothalamus.
Read MoreHave questions about a product?
Contact us to learn more about Meridian’s molecular or immunoassay reagent portfolio. We want to hear from you!
Name | Type | Format | Host/Source | Isotype | Tested Apps | Unit | Catalog | SDS | COA | Request Sample |
---|---|---|---|---|---|---|---|---|---|---|
Human Prolactin Recombinant | Antigen | Purified | E. coli | N/A | CLI | MG | A01467H | SDS | COA | Request Sample |
MAb to Prolactin | Monoclonal | Purified | Mouse | IgG2a,k | EIA,Pr | MG | MAF10-710 | SDS | COA | Request Sample |
MAb to Prolactin | Monoclonal | Purified | Mouse | IgG1,k | EIA,Pr | MG | MAF10-245 | SDS | COA | Request Sample |
MAb to Prolactin | Monoclonal | Purified | Mouse | IgG2a,k | EIA,Pr | MG | MAF10-216 | SDS | COA | Request Sample |
MAb to Prolactin | Monoclonal | Purified | Mouse | IgG1,k | EIA,Pr | MG | MAF10-145 | SDS | COA | Request Sample |
MAb to Prolactin | Monoclonal | Purified | Mouse | IgG1,k | EIA,Pr | MG | MAF10-111 | SDS | COA | Request Sample |
MAb to Human Prolactin | Monoclonal | Purified | Mouse | IgG1,k | Pr,EIA | MG | E20630M | SDS | COA | Request Sample |
MAb to Human Prolactin | Monoclonal | Purified | Mouse | IgG1,k | Pr,EIA | MG | E20122M | SDS | COA | Request Sample |
Hormones & Steroids
Catalogs & Brochures
Meridian Air Dryable Direct StoolHormones & Steroids Catalog
Diagnosis
The biologically active form of prolactin is the 23-kDa monomeric polypeptide secreted by the pituitary gland; however, circulating prolactin exists in a number of additional forms. Big prolactin (60 kDa) and macroprolactin (150 kDa), which are present in serum in varying quantities, can cause apparent hyperprolactinemia, but they have no clinical importance because they exhibit little biological activity. Several studies have shown that prolactin two-site sandwich immunoassays are susceptible to interference from macroprolactin. Current best practice recommends that all sera with increased total prolactin concentrations be subfractionated by PEG precipitation to measure the bioactive monomeric prolactin concentration, a more clinically meaningful variable.
Get In Touch With A Specialist
Have questions about a product? Want to learn more about Meridian’s molecular or immunoassay reagent portfolio? We want to hear from you!