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Prolactin

Prolactin (PRL) is a hormone that is best known for its role in initiating and maintaining lactation in mammals. It is secreted by the anterior pituitary gland and controlled by the hypothalamus.

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8 Results
Name
Type
Format
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Isotype
Tested Apps
Unit
Catalog
SDS
COA
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Prolactin
Purified
Mouse
IgG2a,k
Pr
MG
MAF10-710
Prolactin
Purified
Mouse
IgG1,k
Pr
MG
MAF10-145
Prolactin
Purified
Mouse
IgG2a,k
Pr
MG
MAF10-216
Prolactin
Purified
Mouse
IgG1,k
Pr
MG
MAF10-245
Prolactin
Purified
Mouse
IgG1,k
Pr
MG
MAF10-111
Prolactin
Purified
Mouse
IgG1,k
EIA
MG
E20630M
Prolactin
Purified
Mouse
IgG1,k
EIA
MG
E20122M
Prolactin, Recombinant
Purified
E. coli
N/A
CLI
MG
A01467H

Diagnosis

The biologically active form of prolactin is the 23-kDa monomeric polypeptide secreted by the pituitary gland; however, circulating prolactin exists in a number of additional forms. Big prolactin (60 kDa) and macroprolactin (150 kDa), which are present in serum in varying quantities, can cause apparent hyperprolactinemia, but they have no clinical importance because they exhibit little biological activity. Several studies have shown that prolactin two-site sandwich immunoassays are susceptible to interference from macroprolactin. Current best practice recommends that all sera with increased total prolactin concentrations be subfractionated by PEG precipitation to measure the bioactive monomeric prolactin concentration, a more clinically meaningful variable.

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