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PIVKA II

Protein Induced by Vitamin K Absence or antagonist-II (PIVKA-II) or des-gamma-carboxy prothrombin (DCP) is the precursor and abnormal form of prothrombin which was originally found in patients with hepatocellular carcinoma (HCC). PIVKA-II is thought to be produced as a consequence of an acquired defect of post-translational carboxylation of prothrombin’s precursor. In conjunction with alpha-fetoprotein (AFP), PIVKA-II is used to diagnose and manage HCC. Overall, assays detecting both PIVKA-II and AFP have shown a sensitivity and specificity of 94% and 98.5%, respectively.

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2 Results
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Type
Format
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Unit
Catalog
SDS
COA
Request Sample
MAb to PIVKA-II
Monoclonal
Purified
Mouse
IgG1
EIA
MG
M01343M
MAb to PIVKA-II
Monoclonal
Purified
Mouse
IgG1
EIA
MG
M01344M

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