Chlamydia trachomatis

Chlamydia is the most common sexually transmitted disease and it is caused by the bacterium Chlamydia trachomatis. It affects 5% to 10% of the world’s population and it is particularly common in young adults under 25 years. It is a major public health concern due to its prevalence and potential long-term consequences.

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Chlamydia trachomatis Products (19)

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Name Type Format Host/Source Isotype Tested Apps Unit Catalog SDS COA Request Sample
C. Trachomatis LGV Type-2 EB Antigen Purified Mouse L Cells N/A EIA ML R02121 View SDS View COA Order A Sample
MAb to Chlamydia Species LPS Monoclonal Purified Mouse IgG2b,k EIA MG MAV07-743 View SDS View COA Order A Sample
MAb to Chlamydia Species LPS Monoclonal Purified Mouse IgG2b,k EIA MG MAV07-347 View SDS View COA Order A Sample
MAb to Chlamydia Trachomatis Monoclonal Purified Mouse IgG2a,k EIA,LF,WB MG MAV06-086 View SDS View COA Order A Sample
MAb to Chlamydia Monoclonal Purified Mouse IgG3,l IFA,IHC MG C66436M View COA Order A Sample
MAb to Chlamydia Trachomatis Monoclonal Purified Mouse IgG3,k IFA,IHC MG C66435M View SDS View COA Order A Sample
MAb to Chlamydia Species Monoclonal Purified Mouse IgG1 EIA,IFA,IHC MG C65815M View SDS View COA Order A Sample
MAb to Chlamydia Species Monoclonal Purified Mouse IgG1 EIA,IFA,IHC MG C65168M View COA Order A Sample
MAb to C. trachomatis LPS Monoclonal Purified Mouse IgG LF,Pr MG C01566M View SDS View COA Order A Sample
MAb to C. trachomatis LPS Monoclonal Purified Mouse IgG LF,Pr MG C01565M View SDS View COA Order A Sample
MAb to Chlamydia Species Monoclonal Purified Mouse IgG2b EIA MG C01365M View COA Order A Sample
MAb to Chlamydia Trachomatis Monoclonal Purified Mouse IgG2a EIA,IFA,IHC MG C01363M View SDS View COA Order A Sample
Goat anti C. trachomatis MOMP Polyclonal Purified Goat N/A IFA ML B65266G View SDS View COA Order A Sample
Goat anti C. trachomatis MOMP Polyclonal Biotin Goat N/A IFA ML B65261G View COA Order A Sample
Rabbit anti C. Trachomatis EB Polyclonal Purified Rabbit N/A EIA,IFA ML B65256R View COA Order A Sample
Goat anti C. Trachomatis EB Polyclonal Purified Goat N/A EIA,IFA ML B65256G View COA Order A Sample
Rabbit anti C. Trachomatis EB Polyclonal HRP Rabbit N/A EIA,ICC ML B65253R View COA Order A Sample
Rabbit anti C. Trachomatis EB Polyclonal FITC Rabbit N/A IFA ML B65252R View SDS View COA Order A Sample
Goat anti C. Trachomatis EB Polyclonal FITC Goat N/A IFA ML B65252G View COA Order A Sample

Chlamydia trachomatis

An estimated 100 million Chlamydia trachomatis infections occur annually among sexually active adolescents and young adults in the world. Its prevalence is due to most infections (75% of women and 50% of men) going undiagnosed and spreading the disease unknowingly. Most infections cause minimal to no symptoms, and if left untreated, can lead to non-gonococcal urethritis in men and several inflammatory reproductive tract syndromes in women such as inflammation of the uterine cervix and pelvic inflammatory disease (PID). Over time in women 20% will become infertile, 18% will experience debilitating, chronic pelvic pain, and 9% will have a life-threatening tubal pregnancy. Furthermore, C. trachomatis infection during pregnancy leads to infant conjunctivitis and pneumonia and maternal postpartum endometriosis.

In most cases, chlamydia can be easily treated with antibiotics with a cure rate of 95%. It is recommended that young adults under age 25 and others at high risk (e.g. pregnant women) should be tested for chlamydia once a year even if they are symptom-free.

Diagnosis

Culture testing for C. trachomatis has been the reference standard, however antigen detection using ELISA-based assays, direct fluorescent antibody (DFA) tests and nucleic acid hybridization tests have increased in popularity due to their relative ease-of-use. EIA methods initially developed for the detection of C. trachomatis measured lipopolysaccharide (LPS) antigen expressed by the chlamydial elementary bodies which is common to all four chlamydia species (C. trachomatis, C. pneumoniae, C. psittaci, and C. pecorum). Newer tests for C. trachomatis use antibodies against chlamydial heat shock protein 60 (cHSP60) or the major outer membrane protein (MOMP) which do not cross-react with the other chlamydia species or with other organisms that contain LPS.

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