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Rubella

风疹,又名德国麻疹,它是由披膜病毒属的风疹病毒引起的疾病。这种病毒感染主要侵犯皮肤和淋巴结。它通常在成人和儿童中只造成轻微的症状,但它可以对婴幼儿健康造成极大的破坏。

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姓名 种类 形式 宿主/来源 亚型 主要应用 单位   安全信息表 COA 点击此处订购样品
MAb to Rubella (clone #2-42) Monoclonal Purified Mouse N/A Pr MG EV9526 View SDS View COA Order A Sample
MAb to Rubella (clone #2-6) Monoclonal Purified Mouse N/A Pr MG EV9525 View SDS View COA Order A Sample
MAb to Rubella (E1) Monoclonal Purified Mouse IgG2a EIA,WB MG C66503M View SDS View COA Order A Sample
MAb to Rubella C Protein Monoclonal Purified Mouse IgG1,k EIA,IFA,WB MG C66496M View SDS View COA Order A Sample
Rubella IgM Max antigen   Purified Vero Cells N/A EIA,WB MG 6300 View SDS View COA Order A Sample
Rubella RSVP antigen   Purified Vero Cells N/A EIA,WB MG 6200 View SDS View COA Order A Sample
Rubella Virus Grade IV PBS Ag   Purified Vero Cells N/A EIA,WB,CLI MG 6123 View SDS View COA Order A Sample
Rubella Virus Grade IV Ag   Partially Purified Vero Cells N/A EIA,WB,CLI,Pr MG 6076 View SDS View COA Order A Sample
Rubella Virus Grade III Ag   Purified Vero Cells N/A EIA,WB ML 6075 View SDS View COA Order A Sample
Rubella Virus E2, Recomb.   Purified E. coli N/A EIA,WB MG R18292 View SDS View COA Order A Sample
MAb to Rubella (E1) Monoclonal Purified Mouse IgG2a EIA,WB MG C86323M View SDS View COA Order A Sample
Goat anti-Rubella Virions Polyclonal HRP Goat N/A ICC ML B65704P View SDS View COA Order A Sample
Goat anti-Rubella Virus Virion Polyclonal FITC Goat N/A IFA ML B65703F View SDS View COA Order A Sample
Goat A' Rubella Virus Virions Polyclonal Purified Goat N/A IFA,HI ML B65105G View SDS View COA Order A Sample
mAb to Rubella Monoclonal Purified, Liquid Mouse IgG2a,k EIA,LF MG BN1190 View SDS View COA Order A Sample
mAb to Rubella Monoclonal Purified, Liquid Mouse IgG2a,k EIA,LF MG BN1189 View SDS View COA Order A Sample

风疹病毒

风疹病毒的临床意义在于它如果感染了孕妇可以导致正在发育的胎儿出现先天性风疹综合征(CRS)。自从麻疹- 腮腺炎 - 风疹(MMR)疫苗的广泛推广,全球风疹病例已经明显下降,但是,世界上有些国家还未将这种疫苗列入其计划免疫。在没有广泛接种疫苗的国家中,风疹每隔6-9年就会流行一次。

先天性风疹综合征 (CRS)

A在受孕早期(0-28天)或怀孕前三个月期间如果感染风疹病毒,则病毒通过母体传播给胎儿的风险最高(90%),它可以导致胎儿的先天性风疹综合征(CRS)。从怀孕第14周开始,这种风险降低到52%,而到了孕中期结束时,风险则下降到25%。胎儿的风疹病毒感染常常导致自然流产或胎儿严重畸形,包括心脏,大脑,耳朵或眼睛的畸形。它可造成先天性耳聋,小头畸形和智力低下。在发明风疹病毒疫苗之前,在每1000个活产的婴儿中多达4个婴儿出生时出现先天性风疹综合征。

诊断

风疹病毒可以通过患者的鼻腔,咽喉,尿液和血液样品检测。诊断通常是通过检测在感染风疹病毒4-30天出现的特异性IgM抗体。然而,是否是近期感染的可靠的血清学诊断需要区分患者体内新产生的风疹病毒特异性IgM抗体和体内固有的,重新激活的,或非特异性的IgM抗体。以上的鉴别可以通过附加的试验,如风疹病毒IgG抗体的亲和力试验和免疫印迹分析。

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