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H. pylori Testing

Prevent the Preventable. Manage the Manageable.

H. pylori is 1 of 4 common infections that can lead to cancer- it is preventable with early detection.4

H. pylori Testing

H. pylori is 1 of 4 common infections that can lead to cancer- it is preventable with early detection.4

Only Meridian Provides a Complete H. pylori Active Infection Testing Solution

Meridian Bioscience provides the complete H. pylori testing solution that aligns with diagnostic standards set by the European Helicobacter and Microbiota Study Group (EHMSG) and Maastricht Consensus Reports9 and the American College of Gastroenterology (ACG)10, and other clinical guidelines. Our comprehensive testing menu includes non-invasive tests for active infection like the BreathID® urea breath test (UBT) and stool antigen tests, empowering healthcare professionals with accurate tools for diagnosing and managing H. pylori infections. Choose Meridian Bioscience for a dependable and efficient testing solution tailored to your needs.





Urea Breath Testing Solutions for H. pylori

Noninvasive H. pylori testing from a simple breath sample


The Meridian Bioscience urea breath testing platforms provide unparalleled flexibility and scalability for H. pylori testing across diverse clinical settings. Discover customized solutions catering to the needs of high-volume reference laboratories or compact, near-patient clinical settings.

Stool Antigen Testing Solutions for H. pylori

Noninvasive testing for the detection of H. pylori antigens in stool specimens


The Meridian Bioscience stool antigen testing solutions for H. pylori detection provide reliable, patient-friendly results without invasive procedures. As a leader in cutting-edge medical diagnostics, Meridian’s stool antigen portfolio provides a precise and comprehensive method for identifying Helicobacter pylori infection, a critical factor in the management of gastritis and ulcers.

Learn More About H. pylori

H. pylori is one of the world’s most common bacterial infections and has common GI distress symptoms that are curable. If left untreated, an H. pylori infection can cause chronic gastritis, peptic ulcer disease and even gastric cancer.5

Learn More About H. pylori

H. pylori, or Helicobacter pylori, is a type of bacteria that infects the stomach lining and can lead to various digestive issues, including gastritis and peptic ulcers.

Dyspepsia, commonly known as indigestion, refers to discomfort or pain in the upper abdomen, often accompanied by symptoms like bloating, belching, and nausea. It can be caused by various factors, including overeating, eating too quickly, consuming fatty or spicy foods, stress, or underlying digestive disorders. Dyspepsia can sometimes be a symptom of an H. pylori infection or other gastrointestinal conditions. If symptoms persist or worsen, it’s important to consult a healthcare provider for proper evaluation and management.

H. pylori is usually transmitted through contaminated food, water, or utensils. It can also spread through close contact with an infected person’s saliva or vomit.

Individuals experiencing persistent abdominal pain, bloating, or other symptoms suggestive of a stomach ulcer or gastritis should consider getting tested for H. pylori. Those with a family history of stomach cancer or peptic ulcers may also benefit from H. pylori testing.

Approximately 50% of the world is infected with H. pylori. When left untreated, patients with H. pylori are at risk for long-term consequences such as ulcers and gastric cancer. Gastric cancer accounts for about 1.5% of all new cancers diagnosed in the United States each year. Early detection of H. pylori is vital in establishing appropriate treatment.1,6,7

Guidelines from AGA and ACG recommend a test, treat, and retest approach to confirm the eradication of H. pylori. Active infection tests such as 13C-urea breath tests or stool antigen are recommended rather than serology (antibody). Serology tests cannot determine active H. pylori infection and are no better than a coin toss in predicting the presence of active infection.5,7,8

A healthcare provider will determine the most appropriate treatment for H. pylori. However, treatment may typically involve a combination of antibiotics and acid-suppressing medications to eradicate the bacteria and heal any resulting ulcers. The specific regimen may vary depending on the individual’s health and other factors determined by their healthcare provider.

The ACG/AGA guidelines emphasize the need to test for diagnosis, treatment, and retest to confirm eradication using a non-invasive active infection test for H. pylori infection. H. pylori treatment fails in 1 out of 4 patients. Antibiotic resistance and poor compliance are considered the most common causes of H. pylori treatment failure. There are ways to detect active infection and confirm eradication of an H. pylori infection with our non-invasive active infection tests that deliver trusted results – for lifelong impact.5

Yes, H. pylori infections can recur, especially if the initial treatment was not successful or if the individual is re-exposed to the bacteria. Follow-up testing may be recommended to ensure the infection has been completely eradicated as determined by a healthcare provider.

While it’s not always possible to prevent H. pylori infection, practicing good hygiene, avoiding contaminated food and water, and adopting safe food handling practices can reduce the risk of transmission. Additionally, avoiding close contact with individuals who have active H. pylori infections may help lower the risk.

References:

    1. Fennerty, M. B. Helicobacter pylori: why it still matters in 2005. Cleveland Clinic Journal of Medicine, 2005; 72(Suppl_2), S1-7. https://doi.org/10.3949/ccjm.72.suppl_2.s1.
    2. Centers for Disease Control. MMWR (October 1997) Knowledge About Causes of Peptic Ulcer Disease—United States, March-April 1997. Accessed June 9, 2022.
    3. Helicobacter and Cancer Collaborative Group. Gastric cancer and Helicobacter pylori: a combined analysis of 12 case control studies nested within prospective cohorts. Gut. 2001 Sep;49(3):347-53. doi: 10.1136/gut.49.3.347. PMID: 11511555; PMCID: PMC1728434.
    4. The Lancet. Chronic Disease Management in Aging Populations. Available at https://www.thel ancet.com/journals/lancet/article/PIIS0140-6736(12)60790-9/fulltext. Accessed on June 9, 2022.
    5. Chey WD & Wong BCY. Practice Parameters Committee of the American College of Gastroenterology. American College of Gastroenterology guideline on the management of Helicobacter pylori infection. Am J Gastroenterol, 2007; 102(8):1808-1825
    6. American Cancer Society. Key Statistics for Stomach Cancer. Available at https://www.cancer.org/cancer/stomach-cancer/about/key-statistics.html Accessed June 9, 2022
    7. Chey, W. D., Leontiadis, G. I., Howden, C. W., & Moss, S. F. ACG Clinical Guideline: Treatment of Helicobacter pylori Infection. American Journal of Gastroenterology, 2018; 113(7), p1102. doi: 10.1038/s41395-018-0132-6
    8. Talley, N. J. American Gastroenterological Association Medical Position Statement: Evaluation of Dyspepsia. Gastroenterology, 2005; 129(5):1753–1755. https://doi.org/10.1053/j.gastro.2005.09.019
    9. European Helicobacter and Microbiota Study Group. (n.d.). Guidelines. https://www.ehmsg.org/guidelines
    10. Chey, W. D., Leontiadis, G. I., Howden, C. W., & Moss, S. F. (2017). ACG clinical guideline: Treatment of Helicobacter pylori infection. American College of Gastroenterology. https://acgcdn.gi.org/wp-content/uploads/2018/04/ACG-H.-pylori-Guideline-Summary.pdf

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