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阻断剂和免疫球蛋白

免疫阻断剂用于诊断检测中以减少由非特异性结合和其他干扰而导致的假阳性结果。具体地说,人抗鼠抗体(HAMA)、类风湿因子(RH)和异嗜性抗体(HA)的干扰是酶联免疫和侧向免疫层析检测中最主要的问题,因此在这些检测中需要特殊的阻断剂以减少干扰并确检测结果的准确性。

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迈迪安的阻断剂系列包括主动阻断剂,如TRU Block™, 和被动阻断剂,如小鼠IgG。其中TRU Block™ULTRA(新一代HAMA阻断剂)是经过多年研发目前市面上最强大的免疫分析干扰阻断剂。它可以在侧向引流和ELISA检测中全面抗HAMA, HA和RF的干扰。IVD制造商能够在较低浓度下使用这种主动阻断剂,并实现更高的检测性能。

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