Choose a country to view content specific to your location
Choose a country to view content specific to your location
Alpha-fetoprotein (AFP) is a major plasma protein expressed at high concentrations during fetal development; however, concentrations decrease drastically after birth. When hepatocytes regenerate or proliferate, as seen in liver disease or cancer, AFP expression is activated again, and concentrations increase. Increased serum AFP levels have been used as a clinical biomarker for liver cancer detection, specifically hepatocellular carcinoma (HCC) and germ cell (nonseminoma) carcinoma, since the 1980s. Serum AFP can be fractionated in three forms (AFP-L1, AFP-L2, AFP-L3), with the AFP-L3 fraction being most important in the diagnosis and prognosis of hepatocellular carcinoma.
Contact us to learn more about Meridian’s molecular or immunoassay reagent portfolio. We want to hear from you!
Have questions about a product? Want to learn more about Meridian’s molecular or immunoassay reagent portfolio? We want to hear from you!
By submitting your information in this form, you agree that your personal information may be stored and processed in any country where we have facilities or service providers, and by using our “Contact Us” page you agree to the transfer of information to countries outside of your country of residence, including to the United States, which may provide for different data protection rules than in your country. The information you submit will be governed by our Privacy Statement.
| Type |
|---|
| Format |
| Host/Source |
| Isotype |
| Tested Apps |
| Unit |
| Catalog |
| Buffer |
| Immunogen |
| COFA Description |
| COFA Notes |
| Recombination |
| SDS |
| COA |
| Product Information Sheet |
| Request Sample |
