Next-Generation Sequencing

Meridian’s glycerol-free NGS Library Prep Enzymes enable high-fidelity, high-efficiency library preparation, allowing sequencing kits to be shipped and stored at ambient temperature for greater accessibility. Ambient-temperature NGS assays eliminate cold-chain logistics, expanding access to genomic testing in resource-limited settings. By driving scalable, high-performance sequencing technologies, Meridian is bridging the gap, making NGS-based diagnostics more accessible, efficient, and impactful worldwide.

Next-generation sequencing (NGS) is widely used in clinical diagnostics and precision medicine, with applications spanning oncology, infectious disease, reproductive health, and genetic disorder screening. In cancer care, NGS supports companion diagnostics (CDx) for targeted therapies, minimal residual disease (MRD) monitoring, and liquid biopsy for non-invasive tumor detection. It plays a crucial role in infectious disease diagnostics, identifying pathogens, antimicrobial resistance markers, and tracking viral outbreaks. In reproductive medicine, NGS enables non-invasive prenatal testing (NIPT), carrier screening, and preimplantation genetic testing (PGT). Additionally, it is instrumental in rare disease diagnosis, pharmacogenomics, transplant medicine, and neurological disorder screening, offering personalized insights for treatment decisions. As NGS technology advances, its role in cardiovascular risk assessment, immunogenetics, and population genomics continues to expand, further integrating precision medicine into routine clinical practice.