Choose a country to view content specific to your location

Home » Life Science » Products » Molecular Reagents » Specimen Specific Master Mix

Specimen-specific™ Inhibitor Tolerant Master Mixes

A variety of different inhibitors inherent to clinical and environmental samples can negatively impact the sensitivity and accuracy of a molecular assay. Conventionally, to overcome this, specimens undergo extraction and processing prior to testing. However, extraction technologies are not 100% efficient which can impact the amount of target nucleic acid available for testing, and some inhibitors can co-elute following purification and induce false-negative assay results.
 
Product Filters
Specimen Type
Application
Dryable
High Concentration
Clear All

Products (36)

FiltersClose
NameDetailsApplicationCatalogOrder a SampleSizesDescriptionWet(Liquid)Air-DryableNameGlycerol-FreeLyo-ReadyConcentrationHigh ConcentrationDetailSafety Data SheetCOA/Test ReleaseUser GuideProduct Handling GuideProduct Manual
Lyo-Ready AOF dUTP RNA/DNA qPCR UrineUrine, RNART-qPCRMDX353Order a SampleAvailable in 5 mL (1,000 Rxns) or 50 mL (10,000 Rxns) aliquotsAn optimized RT-qPCR master mix tolerant to inhibitors in urine. Perfect for multiplexing, high throughput assays where there is a greater risk of false positives from cross-over contamination.YesYesLyo-ReadyYesYes4xYes
Lyo-Ready AOF dUTP DNA qPCR UrineUrine, DNAqPCRMDX352Order a SampleAvailable in 5 mL (1,000 Rxns) or 50 mL (10,000 Rxns) aliquotsAn optimized qPCR master mix tolerant to inhibitors in urine. Perfect for multiplexing, high throughput assays where there is a greater risk of false positives from cross-over contamination.YesYesLyo-ReadyYesYes4xYes
Lyo-Ready AOF dUTP RNA/DNA qPCR SalivaSaliva, Sputum, RNART-qPCRMDX333Order a SampleAvailable in 5 mL (1,000 Rxns) or 50 mL (10,000 Rxns) aliquotsAn optimized RT-qPCR master mix tolerant to inhibitors in saliva and sputum. Perfect for multiplexing, high throughput assays where there is a greater risk of false positives from cross-over contamination.YesYesLyo-ReadyYesYes4xYes
Lyo-Ready AOF dUTP DNA qPCR SalivaSaliva, Sputum, DNAqPCRMDX332Order a SampleAvailable in 5 mL (1,000 Rxns) or 50 mL (10,000 Rxns) aliquotsAn optimized qPCR master mix tolerant to inhibitors in saliva and sputum. Perfect for multiplexing, high throughput assays where there is a greater risk of false positives from cross-over contamination.YesYesLyo-ReadyYesYes4xYes
Lyo-Ready AOF dUTP RNA/DNA qPCR BloodBlood, Plasma, Serum, RNART-qPCRMDX323Order a SampleAvailable in 5 mL (1,000 Rxns) or 50 mL (10,000 Rxns) aliquotsAn optimized RT-qPCR master mix tolerant to inhibitors in whole blood and plasma and compatible with all anticoagulants. Perfect for multiplexing, high throughput assays where there is a greater risk of false positives from cross-over contamination.YesYesLyo-ReadyYesYes4xYes
Lyo-Ready AOF dUTP DNA qPCR BloodBlood, Plasma, Serum, DNAqPCRMDX322Order a SampleAvailable in 5 mL (1,000 Rxns) or 50 mL (10,000 Rxns) aliquotsAn optimized qPCR master mix tolerant to inhibitors in whole blood and plasma and compatible with all anticoagulants. Perfect for multiplexing, high throughput assays where there is a greater risk of false positives from cross-over contamination.YesYesLyo-ReadyYesYes4xYes
Lyo-Ready Direct RNA/DNA LAMP Urine, 4xUrine, RNART-LAMPMDX155Order a SampleAvailable in 5 mL (1,000 Rxns) or 50 mL (10,000 Rxns) aliquotsInhibitor tolerance to 20% urine. Perfect for multiplexing and fast cycling conditions. Used in the detection of urinary track infections, STD, tropical diseases, cancer screening, bladder and prostate cancer.YesYesLyo-ReadyYesYes4xYes
Lyo-Ready Direct DNA LAMP Urine, 4xUrine, DNALAMPMDX154Order a SampleAvailable in 5 mL (1,000 Rxns) or 50 mL (10,000 Rxns) aliquotsInhibitor tolerance to 20% urine. Perfect for multiplexing and fast cycling conditions. Used in the detection of urinary track infections, STD, tropical diseases, cancer screening, bladder and prostate cancer.YesYesLyo-ReadyYesYes4xYes
Lyo-Ready Genotyping Direct qPCR Urine, 4xUrine, DNASNP GenotypingMDX158Order a SampleAvailable in 1,000 Unit or 10,000 Unit aliquotsInhibitor tolerance to 20% urine. Compatible with all dual-label probe chemistries for detection of genetic variants, such as single nucleotide and copy number variants, to give highly reproducible allelic discrimination.YesYesLyo-ReadyYesYes4xYes
Lyo-Ready Genotyping Direct qPCR FFPE, 4xFFPE, DNASNP GenotypingMDX168Order a SampleAvailable in 1,000 Unit or 10,000 Unit aliquotsBetter extraction buffers and greater tolerance to crude FFPE samples. Compatible with all dual-label probe chemistries for detection of genetic variants, such as single nucleotide and copy number variants, to give highly reproducible allelic discrimination.YesYesLyo-ReadyYesYes4xYes
Lyo-Ready Direct RNA/DNA qPCR Stool, 4xStool, RNART-qPCRMDX143Order a SampleAvailable in 5 mL (1,000 Rxns) or 50 mL (10,000 Rxns) aliquotsInhibitor tolerance to 5% stool, 2 mg/mL bile salt and 40% Cary Blair media. Perfect for multiplexing and fast cycling conditions. Used in the detection of IBD, cancer, fecal microbiota and bacterial and viruses.YesYesLyo-ReadyYesYes4xYes
Lyo-Ready Direct RNA/DNA qPCR Urine, 4xUrine, RNART-qPCRMDX153Order a SampleAvailable in 5 mL (1,000 Rxns) or 50 mL (10,000 Rxns) aliquotsInhibitor tolerance to 20% urine. Perfect for multiplexing and fast cycling conditions. Used in the detection of urinary track infections, STD, tropical diseases, cancer screening, bladder and prostate cancer.YesYesLyo-ReadyYesYes4xYes
Lyo-Ready Direct DNA qPCR Urine, 4xUrine, DNAqPCRMDX152Order a SampleAvailable in 5 mL (1,000 Rxns) or 50 mL (10,000 Rxns) aliquotsInhibitor tolerance to 20% urine. Perfect for multiplexing and fast cycling conditions. Used in the detection of urinary track infections, STD, tropical diseases, cancer screening, bladder and prostate cancer.YesYesLyo-ReadyYesYes4xYes
Air-Dryable Direct RNA/DNA qPCR Urine, 4xUrine, RNART-qPCRMDX151Order a SampleAvailable in 5 mL (1,000 Rxns) or 50 mL (10,000 Rxns) aliquotsInhibitor tolerance to 20% urine. Perfect for multiplexing and fast cycling conditions. Used in the detection of urinary track infections, STD, tropical diseases, cancer screening, bladder and prostate cancer.YesYesAir-DryableYesNo4xYes
Air-Dryable Direct DNA qPCR Urine, 4xUrine, DNAqPCRMDX150Order a SampleAvailable in 5 mL (1,000 Rxns) or 50 mL (10,000 Rxns) aliquotsInhibitor tolerance to 60% urine. Perfect for multiplexing and fast cycling conditions. Used in the detection of urinary track infections, STD, tropical diseases, cancer screening, bladder and prostate cancer.YesYesAir-DryableYesNo4xYes
Lyo-Ready Genotyping Direct qPCR Stool, 4xStool, DNASNP GenotypingMDX148Order a SampleAvailable in 1,000 Unit or 10,000 Unit aliquotsInhibitor tolerance to 20% stool. Compatible with all dual-label probe chemistries for detection of genetic variants, such as single nucleotide and copy number variants, to give highly reproducible allelic discrimination.YesYesLyo-ReadyYesYes4xYes
Lyo-Ready Direct RNA/DNA LAMP Stool, 4xStool, RNART-LAMPMDX145Order a SampleAvailable in 5 mL (1,000 Rxns) or 50 mL (10,000 Rxns) aliquotsInhibitor tolerance to 5% stool, 2 mg/mL bile salt and 40% Cary Blair media. Perfect for multiplexing and fast cycling conditions. Used in the detection of IBD, cancer, fecal microbiota and bacterial and viruses.YesYesLyo-ReadyYesYes4xYes
Lyo-Ready Direct DNA LAMP Stool, 4xStool, DNALAMPMDX144Order a SampleAvailable in 5 mL (1,000 Rxns) or 50 mL (10,000 Rxns) aliquotsInhibitor tolerance to 20% stool, 2 mg/mL bile salt and 40% Cary Blair media. Perfect for multiplexing and fast cycling conditions. Used in the detection of IBD, cancer, fecal microbiota and bacterial and viruses.YesYesLyo-ReadyYesYes4xYes
Lyo-Ready Direct DNA qPCR Stool, 4xStool, DNAqPCRMDX142Order a SampleAvailable in 5 mL (1,000 Rxns) or 50 mL (10,000 Rxns) aliquotsInhibitor tolerance to 20% stool, 2 mg/mL bile salt and 40% Cary Blair media. Perfect for multiplexing and fast cycling conditions. Used in the detection of IBD, cancer, fecal microbiota and bacterial and viruses.YesYesLyo-ReadyYesYes4xYes
Lyo-Ready Direct RNA/DNA LAMP Blood, 4xBlood, Plasma, Serum, RNART-LAMPMDX125Order a SampleAvailable in 5 mL (1,000 Rxns) or 50 mL (10,000 Rxns) aliquotsInhibitor tolerance to 10% whole blood, 10% plasma, compatible with all anticoagulants. Perfect for multiplexing and fast cycling conditions. Used in the detection of blood pathogens and liquid biopsy applications.YesYesLyo-ReadyYesYes4xYes
Air-Dryable Direct DNA LAMP Blood, 4xBlood, Plasma, Serum, DNALAMPMDX126Order a SampleAvailable in 5 mL (1,000 Rxns) or 50 mL (10,000 Rxns) aliquotsInhibitor tolerance to 10% whole blood, 10% plasma, compatible with all anticoagulants. Perfect for multiplexing and fast cycling conditions. Used in the detection of blood pathogens and liquid biopsy applications.YesYesAir-DryableYesNo4xYes
Lyo-Ready Genotyping Direct qPCR Blood, 4xBlood, Plasma, Serum, DNASNP GenotypingMDX128Order a SampleAvailable in 1,000 Unit or 10,000 Unit aliquotsInhibitor tolerance to 10% whole blood, 20% plasma. Compatible with all dual-label probe chemistries for detection of genetic variants, such as single nucleotide and copy number variants, to give highly reproducible allelic discrimination.YesYesLyo-ReadyYesYes4xYes
Air-Dryable Direct DNA qPCR Saliva, 4xSaliva, Sputum, DNAqPCRMDX130Order a SampleAvailable in 5 mL (1,000 Rxns) or 50 mL (10,000 Rxns) aliquotsInhibitor tolerance to 60% crude saliva, sputum or mucin samples and 50% UTM. Perfect for multiplexing and fast cycling conditions. Used in the detection of a broad range of diseases, including cancer, respiratory viruses and bacterial infections.YesYesAir-DryableYesNo4xYes
Air-Dryable Direct RNA/DNA qPCR Saliva, 4xSaliva, Sputum, RNART-qPCRMDX131Order a SampleAvailable in 5 mL (1,000 Rxns) or 50 mL (10,000 Rxns) aliquotsInhibitor tolerance to 60% crude saliva, sputum or mucin samples and 50% UTM. Perfect for multiplexing and fast cycling conditions. Used in the detection of a broad range of diseases, including cancer, respiratory viruses and bacterial infections.YesYesAir-DryableYesNo4xYes
Lyo-Ready Direct DNA qPCR Saliva, 4xSaliva, Sputum, DNAqPCRMDX132Order a SampleAvailable in 5 mL (1,000 Rxns) or 50 mL (10,000 Rxns) aliquotsInhibitor tolerance to 60% crude saliva, sputum or mucin samples and 50% UTM. Perfect for multiplexing and fast cycling conditions. Used in the detection of a broad range of diseases, including cancer, respiratory viruses and bacterial infections.YesYesLyo-ReadyYesYes4xYes
Lyo-Ready Direct RNA/DNA qPCR Saliva, 4xSaliva, Sputum, RNART-qPCRMDX133Order a SampleAvailable in 5 mL (1,000 Rxns) or 50 mL (10,000 Rxns) aliquotsInhibitor tolerance to 60% crude saliva, sputum or mucin samples and 50% UTM. Perfect for multiplexing and fast cycling conditions. Used in the detection of a broad range of diseases, including cancer, respiratory viruses and bacterial infections.YesYesLyo-ReadyYesYes4xYes
Lyo-Ready Direct DNA LAMP Saliva, 4xSaliva, Sputum, DNALAMPMDX134Order a SampleAvailable in 5 mL (1,000 Rxns) or 50 mL (10,000 Rxns) aliquotsInhibitor tolerance to 60% crude saliva, sputum or mucin samples and 50% UTM. Perfect for multiplexing and fast cycling conditions. Used in the detection of a broad range of diseases, including cancer, respiratory viruses and bacterial infections.YesYesLyo-ReadyYesYes4xYes
Lyo-Ready Direct RNA/DNA LAMP Saliva, 4xSaliva, Sputum, RNART-LAMPMDX135Order a SampleAvailable in 5 mL (1,000 Rxns) or 50 mL (10,000 Rxns) aliquotsInhibitor tolerance to 60% crude saliva, sputum or mucin samples and 50% UTM. Perfect for multiplexing and fast cycling conditions. Used in the detection of a broad range of diseases, including cancer, respiratory viruses and bacterial infections.YesYesLyo-ReadyYesYes4xYes
Air-Dryable Direct DNA qPCR Stool, 4xStool, DNAqPCRMDX140Order a SampleAvailable in 5 mL (1,000 Rxns) or 50 mL (10,000 Rxns) aliquotsInhibitor tolerance to 20% stool, 2 mg/mL bile salt and 40% Cary Blair media. Perfect for multiplexing and fast cycling conditions. Used in the detection of IBD, cancer, fecal microbiota and bacterial and viruses.YesYesAir-DryableYesNo4xYes
Air-Dryable Direct RNA/DNA qPCR Stool, 4xStool, RNART-qPCRMDX141Order a SampleAvailable in 5 mL (1,000 Rxns) or 50 mL (10,000 Rxns) aliquotsInhibitor tolerance to 5% stool, 2 mg/mL bile salt and 40% Cary Blair media. Perfect for multiplexing and fast cycling conditions. Used in the detection of IBD, cancer, fecal microbiota and bacterial and viruses.YesYesAir-DryableYesNo4xYes
Air-Dryable Direct DNA qPCR Blood, 4xBlood, Plasma, Serum, DNAqPCRMDX092Order a SampleAvailable in 5 mL (1,000 Rxns) or 50 mL (10,000 Rxns) aliquotsInhibitor tolerance to 20% whole blood, 20% plasma, compatible with all anticoagulants. Perfect for multiplexing and fast cycling conditions. Used in the detection of blood pathogens and liquid biopsy applications.YesYesAir-DryableYesNo4xYes
Lyo-Ready Direct DNA LAMP Blood, 4xBlood, Plasma, Serum, DNALAMPMDX124Order a SampleAvailable in 5 mL (1,000 Rxns) or 50 mL (10,000 Rxns) aliquotsInhibitor tolerance to 20% whole blood, 20% plasma, compatible with all anticoagulants. Perfect for multiplexing and fast cycling conditions. Used in the detection of blood pathogens and liquid biopsy applications.YesYesLyo-ReadyYesYes4xYes
Lyo-Ready Direct RNA/DNA qPCR Blood, 4xBlood, Plasma, Serum, RNART-qPCRMDX123Order a SampleAvailable in 5 mL (1,000 Rxns) or 50 mL (10,000 Rxns) aliquotsInhibitor tolerance to 10% whole blood, 10% plasma, compatible with all anticoagulants. Perfect for multiplexing and fast cycling conditions. Used in the detection of blood pathogens and liquid biopsy applications.YesYesLyo-ReadyYesYes4xYes
Lyo-Ready Direct DNA qPCR Blood, 4xBlood, Plasma, Serum, DNAqPCRMDX122Order a SampleAvailable in 5 mL (1,000 Rxns) or 50 mL (10,000 Rxns) aliquotsInhibitor tolerance to 20% whole blood, 20% plasma, compatible with all anticoagulants. Perfect for multiplexing and fast cycling conditions. Used in the detection of blood pathogens and liquid biopsy applications.YesYesLyo-ReadyYesYes4xYes
Air-Dryable Direct RNA/DNA qPCR Blood, 4xBlood, Plasma, Serum, RNART-qPCRMDX121Order a SampleAvailable in 5 mL (1,000 Rxns) or 50 mL (10,000 Rxns) aliquotsInhibitor tolerance to 10% whole blood, 10% plasma, compatible with all anticoagulants. Perfect for multiplexing and fast cycling conditions. Used in the detection of blood pathogens and liquid biopsy applications.YesYesAir-DryableYesNo4xYes
Air-Dryable Direct DNA qPCR Plant, 4xPlant, DNAqPCRMDX116Order a SampleAvailable in 5 mL (1,000 Rxns) or 50 mL (10,000 Rxns) aliquotsNo need for extraction, compatible with 25% Plant lysate (SDS, NaOH). Perfect for multiplexing and fast cycling conditions for in-field qPCR testing. Used for genotyping and transgene or pathogenic detection.YesYesAir-DryableYesNo4xYes

Not seeing what you’re looking for? Inquire about a new product

Sample Specific Inhibitor Tolerant qPCR and RT-qPCR Formulations

In developing universal inhibitor tolerant qPCR and RT-qPCR mixes, a compromise is required to accommodate all of the different types of inhibitors, this reduces sensitivity of the quantitative PCR. Meridian has therefore developed sample specific inhibitor tolerant qPCR and RT-qPCR formulations, designed to be used for direct amplification from crude lysates or inhibitor-rich samples either from blood, saliva, urine or stool. The ability of these mixes to tolerate the high level of PCR inhibitors present in these different sample types allows the development of simpler, faster multiplex qPCR assays that require minimal sample processing and fast turn-around times (TAT). This makes them ideal for liquid biopsy and point of care testing (POCT), where speed, sensitivity, and reproducibility are essential.

The mixes can be used as wet mixes or dried by lyophilization or air-drying, there are several advantages to this, including room temperature shipping and storage, extended shelf-life, and increased flexibility in the sample volume.

Other Specimens Used for Laboratory Diagnostic Testing

Interested to learn more about COVID/Flu/RSV multiplex testing?

How to Air-Dry an Assay

See how easy it is to Air-Dry an assay.

Click the play button on the left.

Why We Are Second To None

Meridian offers diagnostic manufacturers the complete solution with over 3,000 antigens and antibodies covering more than 500 diseases and an extensive range of specialty qPCR/RT-qPCR master mixes and molecular enzymes all manufactured under ISO13485 regulations.

Large Sample Size

Lot Reservation

ISO13485

World-Class Customer Service

Catalogs & Brochures

Master Mixes for Molecular Ambient-Temperature Stable Assays

Master Mixes for Molecular Ambient-Temperature Stable Assays

Air-Dryable Mixes

Air-Dryable Mixes

Specimen-specific™ and Universal qPCR & LAMP Master Mixes for Ultra-Sensitive Detection

Specimen-specific™ and Universal qPCR & LAMP Master Mixes for Ultra-Sensitive Detection

Lyo-Ready & Air-Dryable LAMP & RT-LAMP Master Mixes

Lyo-Ready & Air-Dryable LAMP & RT-LAMP Master Mixes

Get In Touch With A Specialist

Have questions about a product? Want to learn more about Meridian’s molecular or immunoassay reagent portfolio? We want to hear from you!

By submitting your information in this form, you agree that your personal information may be stored and processed in any country where we have facilities or service providers, and by using our “Contact Us” page you agree to the transfer of information to countries outside of your country of residence, including to the United States, which may provide for different data protection rules than in your country. The information you submit will be governed by our Privacy Statement.

Learn More About Us

Boost your assay robustness with our inhibitor-tolerant qPCR mixes—learn more now!