Meridian’s Approach to Ambient-Temperature Stabilization
At Meridian, we help assay developers create ambient temperature-stable assays without compromising performance—thanks to our specialized stabilization services for key molecular reagents like enzymes, dUTPs, and master mixes. Whether through lyophilization, air-drying, or our proprietary glycerol-free enzyme technologies and lyo-ready mixes, we deliver tailored solutions that extend shelf life, enhance sensitivity, and eliminate cold-chain requirements. Our expertise streamlines workflows, reduces costs, and speeds up time-to-market for qPCR, isothermal amplification, and NGS assays—fueling innovation in infectious disease, oncology, and beyond.
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Glycerol-Free Enzyme Development
We stabilize YOUR enzymes. Whether you’re using Meridian reagents or your own proprietary enzymes, we customize glycerol-free solutions to make them compatible with ambient temperature-stable formats—without compromising performance.
Glycerol is commonly used to protect enzymes during storage, but it interferes with lyophilization and air-drying. By removing glycerol and applying our formulation expertise, we help preserve enzyme activity while enabling room-temperature storage, simplified logistics, and greater flexibility in assay development and commercialization.
Custom Master Mix Optimization
We stabilize YOUR mix. Whether you’re using a Meridian master mix or your own formulation, we tailor it for ambient temperature stability—ready for lyophilization, air-drying, or other demanding applications.
Our flexible optimization services preserve mix integrity and functionality, ensuring consistent performance across assay runs and storage conditions. From minor refinements to complete re-formulations, we help prepare your mix for seamless commercialization. We support:
- Lyophilization or air-drying compatibility
- dUTP incorporation
- Platform integration (e.g., microfluidics, POC systems)
- Assay-specific enhancements for qPCR, isothermal amplification, NGS, and more
