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HER2 Antibodies and Antigens

Receptor tyrosine-protein kinase erbB-2, also known as HER2/Neu (human epidermal growth factor receptor 2), is a member of the human epidermal growth factor receptor family. Overexpression of HER2/Neu plays an essential role in the development and progression of specific subtypes of breast cancer. Approximately 15%-20% of all newly diagnosed breast cancers are HER2-positive, and HER2 testing identifies patients who would benefit from HER2-targeted therapies, such as trastuzumab (Herceptin), lapatinib (Tykerb), pertuzumab (Perjeta), and T-DM1 (Kadcylapatients).

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HER2 Products (5)

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	Name	Type	Format	Host/Source	Isotype	Tested Apps	Unit	Catalog	Buffer	Immunogen	Recombinant	Description	Notes	Safety Data Sheet	COA/Test Release	Product Information Sheet	New Product	Recommended Product	Order a Sample
	HER2/ErbB2 Recombinant	Antigen	Purified	HEK293 cells	N/A	EIA	MG	R01605	Prior to lyophilization: Phosphate Buffer Saline, pH 7.4 with Mannitol or Trehalose.		Yes	HER2 / ErbB2 Recombinant Human Epidermal Growth Factor Receptor 2 (HER2) Recombinant Also known as: CD340, HER2/neu and c-erbB2.		Safety Data Sheet —	COA/Test Release	—	0	0
	MAb to Erbb-2, Her2/neu	Monoclonal	Purified	Mouse	IgG2a	EIA	MG	M01298M	Phosphate Buffered Saline, pH 7.4	Peptide coupled with APP.	No	MAb to ERBB-2, HER2/neu Monoclonal Antibody to erythroblastic leukemia viral oncogene homolog 2 (erbB-2, HER2/neu).		Safety Data Sheet —	COA/Test Release	—	0	0
	MAb to Erbb-2, Her2/neu	Monoclonal	Purified	Mouse	IgG2a	EIA	MG	M01299M	PBS, pH 7.4	Peptide coupled with APP.	No	MAb to ERBB-2, HER2/neu Monoclonal Antibody to erythroblastic leukemia viral oncogene homolog 2 (ERBB-2, HER2/neu).		Safety Data Sheet —	COA/Test Release	—	0	0
	MAb to Erbb-2, Her2/neu	Monoclonal	Purified	Mouse	IgG2a	EIA	MG	M01296M	Phosphate Buffered Saline, pH 7.4	Peptide coupled with APP.	No	MAb to ERBB-2, HER2/neu Monoclonal Antibody to erythroblastic leukemia viral oncogene homolog 2 (ERBB-2, HER2/neu).		Safety Data Sheet —	COA/Test Release	—	0	0
	MAb to Erbb-2, Her2/neu	Monoclonal	Purified	Mouse	IgM	EIA	MG	M01297M	PBS, pH 7.4	Peptide coupled with APP.	No	MAb to ERBB-2, HER2/neu Monoclonal Antibody to erythroblastic leukemia viral oncogene homolog 2 (ERBB-2, HER2/neu).		Safety Data Sheet —	COA/Test Release	—	0	0

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Type
Format
Host/Source
Isotype
Tested Apps
Unit
Catalog
Buffer
Immunogen
COFA Description
COFA Notes
Recombination
SDS
COA
Product Information Sheet
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