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Epidermal Growth Factor Receptor (EGFR)

Epidermal growth factor receptor (EGFR) is a tyrosine kinase that stimulates proliferation and differentiation by binding its ligand, epidermal growth factor (EGF). Dysregulation and mutations of EGFR have been documented in many solid tumor disease states such as head and neck, breast, renal, colon, glioblastoma multiforme, and non-small-cell lung cancer. Clinical diagnosis of EGFR upregulation or mutations is important in determining which tumors will respond to cancer therapy using tyrosine kinase inhibitors. EGFR upregulation is usually diagnosed by serologic testing and EFGR mutations by real-time PCR or next-generation sequencing.

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Clear Results
5 Results
Name
Type
Format
Host/Source
Isotype
Tested Apps
Unit
Catalog
SDS
COA
Request Sample
HER2/ErbB2 Recombinant
Antigen
Purified
HEK293 cells
N/A
EIA
MG
R01605
MAb to EGFR pS1047
Monoclonal
Purified
Mouse
IgG1
EIA, IB, ICC, IP
MG
K67190M
MAb to EGFR,activated pTyr1173
Monoclonal
Purified
Mouse
IgG1,k
EIA, IB, ICC, IP
MG
K67902M
MAb to EGFR, pTyr 845
Monoclonal
Purified
Mouse
IgG1
EIA, IP
MG
K67123M
MAb to EGFR, pTyr 1045
Monoclonal
Purified
Mouse
IgG1
EIA
MG
K67112M

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