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EGFR

Epidermal growth factor receptor (EGFR) is a tyrosine kinase that stimulates proliferation and differentiation by binding its ligand, epidermal growth factor (EGF). Dysregulation and mutations of EGFR have been documented in many solid tumor disease states such as head and neck, breast, renal, colon, glioblastoma multiforme, and non-small-cell lung cancer. Clinical diagnosis of EGFR upregulation or mutations is important in determining which tumors will respond to cancer therapy using tyrosine kinase inhibitors. EGFR upregulation is usually diagnosed by serologic testing and EFGR mutations by real-time PCR or next-generation sequencing.

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EGFR Products (4)

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Name Type Format Host/Source Isotype Tested Apps Unit Catalog Buffer Immunogen Recombinant Description Notes SDS COA New Product Recommended Product Order a Sample
MAb to EGFR,activated pTyr1173 Monoclonal Purified Mouse IgG1,k EIA,IP,IB,ICC MG K67902M No View SDS View COA 0 Order a Sample
MAb to EGFR pS1047 Monoclonal Purified Mouse IgG1 EIA,ICC,IB,IP MG K67190M No View SDS View COA 0 Order a Sample
MAb to EGFR, pTyr 845 Monoclonal Purified Mouse IgG1 EIA,IP MG K67123M No View SDS View COA 0 Order a Sample
MAb to EGFR, pTyr 1045 Monoclonal Purified Mouse IgG1 EIA,IB,IP MG K67112M No View SDS View COA 0 Order a Sample

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