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Custom Formulation Services​

Glycerol-Free Reagent Development for qPCR, Isothermal Amplifications and NGS

Meridian’s Approach​ to Ambient-Temperature Stabilization

At Meridian, we are known for delivering high-performance molecular reagents and innovative solutions, to fit the diverse needs of our IVD customers. Our specialized molecular services include custom glycerol-free formulations to enable lyophilization and air-dryable formats of key molecular reagents. Our stabilization technologies ensure ambient-temperature shipping and storage, extending shelf life and enhancing sustainability without compromising on performance, vital for both point-of-care and high-throughput applications in the IVD market.​

Why Choose Meridian?

Request Information About Meridian's Custom Services for Ambient-Temperature Stabilization

Glycerol-Free Enzyme Development​

Glycerol is commonly used to stabilize enzymes during their storage to prevent damage; however, it can interfere with lyophilization. Glycerol-free formulations are used to ensure compatibility with lyophilization or air-drying while preserving the performance and stability of the enzyme activity to facilitate storage and transport conditions, allowing more flexibility during development and cost saving during commercialization. ​

At Meridian, we have many years of expertise in developing glycerol-free enzymes for qPCR, LAMP and NGS. We can take an existing enzyme from our catalog, source an enzyme, or take one of your proprietary enzymes and create a glycerol-free format using your own specifications. ​

Custom Master Mix Optimization​

We can take any of Meridian’s master mixes and further optimize it to your specific workflow and assay, and if required even transforming the assay into an ambient temperature stable format.​
For example:
  • For lyophilization​
  • For air-drying​
  • Incorporation of dUTP​
  • Integration to platform​

Whatever the technology is, qPCR, LAMP, NGS, NASBA etc.​

Learn more about Meridian's Custom Formulation Services