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Carba C Testing

The Revogene Carba C assay provides healthcare systems with a diagnostic solution to enable early detection and management of Carbapenem-Resistant Enterobacterales (CRE) from isolated colonies of Enterobacteriaceae, Acinetobacter baumannii, or Pseudomonas aeruginosa.

Catalog Number: 410500

Why Revogene Carba C?

Carbapenem-Resistant Enterobacterales (CRE) infections are hazardous to our patients and alarming for healthcare systems. The CDC has deemed CRE an urgent public health threat that requires immediate and aggressive action. 1

Early identification and isolation of colonized or infected patients is key to limiting the spread of these organisms in healthcare settings and to help in better guidance of treatment.


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    Efficient workflow - Sample to result in 3 easy steps

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    Flexible platform - Run multiple assays with different sample types on a single run

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    Total solution - Can be paired with Meridian immunoassays for a scalable testing solution

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    Platform for growth - Single analyte and multiplex testing capability

Test Procedure

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  • Transfer colonies to obtain a standardized 0.5 MacFarland suspension.
  • Vortex the 0.5 MacFarland suspension at maximum speed for 15 seconds.
  • Using a micropipette, aspirate 15 µL of MacFarland suspension and dispense into the Sample Buffer Tube (SBT).
  • Vortex the SBT at high speed for 15 seconds.
  • Unseal the pouch containing the Revogene® Carba C PIE.

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  • Using the Disposable Transfer Tool (DTT), aspirate the Sample Buffer (SB) by squeezing the entire bulb until the liquid level is anywhere between the two lines on the DTT.
  • Discharge the specimen completely into the Sample Loading Chamber of the PIE.
  • Close the cap of the Sample Loading Chamber tightly.

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  • Start the test run by navigating to the menu. Select Revogene® Carba C. Follow the onscreen instructions to load the patient test PIE.
  • Load the remaining patient tests. If less than eight (8) PIEs are being tested, load MOCK PIES in the carousel in the remaining positions.
  • Scan the retention ring and place it on the carousel.

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  • Close the instrument lid with both hands and ensure the lid lock engages.
  • Select to initiate the test and walk away.
  • The lid opens when the run is complete.
  • Remove all PIEs including MOCK PIES after the run.
  • Tap the icon to see test results.

Early detection is key for CRE infection prevention and control. The CDC recommends “detecting and protecting” through early identification of CRE carriers, followed by prevention of transmission through implementation of infection control precautions.

CDC recommends “detecting and protecting”

Support & Documents

Downloadable PDFs


Revogene Carba C – 87150 x 5




4. Neuner, E. & Gallagher J., 2017. Pharmacodynamic and pharmacokinetic considerations in the treatment of critically ill patients infected with carbapenem-resistant Enterobacteriaceae. Virulence. 8(4):440-452.

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