Avoiding immunoassay interference requires blockers to be included in every immunoassay. Historically, animal-based interference blockers have been used to improve assay accuracy; however, they are susceptible to cross-reactivity with assay reagents, lot-to-lot variability, and supply shortages – as seen during the COVID-19 pandemic. Meridian’s new animal-free commercial blockers, K-BlockTM and Mouse-FREE IgG, are the next-generation solution for blocking HAMA/RF/HA that overcomes the ethical concerns and supply problems in using animal-derived blockers.

Imagine diagnostic assays that can be shipped and stored at room temperature—no refrigeration, no freezing, no compromise in performance. In this blog, discover how Meridian is advancing molecular testing by engineering high-performing, glycerol-free enzymes designed for ambient-temperature stability and lyophilization. Learn how these innovative formulations eliminate cold chain barriers, enhance global diagnostic access, and maintain exceptional sensitivity and specificity—even in the most remote settings. Read on to explore the science behind glycerol-free buffers and how Meridian’s custom solutions can power your next-generation assay development.

Molecular point-of-care (POC) diagnostics offer speed and accuracy, but challenges like cold-chain dependency and complex workflows often limit their use in remote or resource-limited settings. This webinar explores how innovative molecular reagents are overcoming these barriers by enabling ambient-temperature stability and streamlining assay workflows. Learn about cutting-edge advances in qPCR and isothermal technologies specifically designed for POC applications—and discover how eliminating cold-chain requirements can expand access and improve reliability in the field. Watch now to gain expert insights that can help accelerate your assay development.

The lingering effects of COVID-19 extend far beyond respiratory symptoms. Elevated levels of autoantibodies like rheumatoid factor (RF) have emerged as a hidden challenge for diagnostic assay developers, causing increased interference and false positives in immunoassays. This blog explores how the pandemic reshaped the immune landscape—and why assay interference is now a critical concern. From RF’s unique mechanisms of disruption to practical mitigation strategies and Meridian’s advanced blocking solutions, this article provides the insights you need to maintain assay reliability in a post-COVID world.