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Histones are proteins that are a part of chromatin and aid in the coiling of DNA. Certain autoimmune conditions cause the development of histone autoantibodies, which are a type of antinuclear antibodies (ANA). Antibodies to histones are usually found in people with drug-induced lupus, but they can also be found in people with systemic lupus. Detection of anti-histone antibodies is essential for diagnosing and caring for patients at risk of drug-induced lupus or in managing ongoing autoimmune conditions.
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| Name | Type | Format | Host/Source | Isotype | Tested Apps | Unit | Catalog | Buffer | Immunogen | Recombinant | Description | Notes | Safety Data Sheet | COA/Test Release | Product Information Sheet | New Product | Recommended Product | Order a Sample | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Human anti Histone (whole) | Monoclonal | Purified | Human | N/A | EIA,ID | ML | K07111H | Lyophilized from 0.01 M Phosphate, 0.13 M Sodium Chloride, pH 7.2. | No | Human Antibody to Histone (Whole) | Safety Data Sheet — | COA/Test Release | — | 0 | 0 | |||||
| Histone antigen | Antigen | Purified | Bovine | N/A | EIA | MG | A01673B | 20 mM HEPES-Sodium Hydroxide (NaOH), pH 7.5, 1.6 mM EDTA, 2.0 M Sodium Chloride, 0.08 mM PMSF, 0.16 mM DTT, 20% (v/v) Glycerol. | H3atolecularidh1 kDa-01 kDa Proprietary | No | Molecular Weight: 30-35 kDa (H1 Histones) 10-16 kDa (Core Histones) | Safety Data Sheet — | COA/Test Release | — | 0 | 0 |
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