The jo-1 antigen is histidyl-transfer ribonucleic acid (tRNA) synthetase which aids in the incorporation of histidine residues into proteins. Anti-Jo-1 autoantibodies are found in autoimmune connective tissue diseases, and they bind to conformational epitopes of the enzyme protein and inhibit its catalytic activity in vitro. Jo 1 antibodies are a marker for polymyositis and occur most commonly in myositis patients who also have interstitial lung disease.
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|Name||Type||Format||Host/Source||Isotype||Tested Apps||Unit||Catalog||SDS||COA||Request Sample|
|Human anti Jo-1 antigen||Monoclonal||Purified||Human Donor||N/A||EIA,ID||ML||K07101H||SDSSafety Data Sheet||COACERTIFICATE OF ANALYSIS||Request Sample|
|Jo-1 antigen||Antigen||Purified||Bovine Thymus||N/A||EIA||MG||A3C302B||SDSSafety Data Sheet||COACERTIFICATE OF ANALYSIS||Request Sample|
|Jo-1 antigen||Antigen||Aff.Pur.||Rabbit Thymus||N/A||EIA||UT||A07302B||SDSSafety Data Sheet||COACERTIFICATE OF ANALYSIS||Request Sample|
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