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AFP

Alpha-fetoprotein (AFP) is a major plasma protein expressed at high concentrations during fetal development; however, concentrations decrease drastically after birth. When hepatocytes regenerate or proliferate, as seen in liver disease or cancer, AFP expression is activated again, and concentrations increase. Increased serum AFP levels have been used as a clinical biomarker for liver cancer detection, specifically hepatocellular carcinoma (HCC) and germ cell (nonseminoma) carcinoma, since the 1980s. Serum AFP can be fractionated in three forms (AFP-L1, AFP-L2, AFP-L3), with the AFP-L3 fraction being most important in the diagnosis and prognosis of hepatocellular carcinoma.

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AFP Products (13)

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Name Type Format Host/Source Isotype Tested Apps Unit Catalog SDS COA Request Sample
Human AFP antigen Grade Antigen Aff.Pur. Culture N/A WB MG A32260H View SDS View COA Order A Sample
AFP >=95% Pure Antigen Purified Human N/A EIA MG A01695H View SDS View COA Order A Sample
Human AFP antigen Grade Antigen Purified Human Cord Serum N/A EIA,WB MG A01407H View SDS View COA Order A Sample
Human AFP antigen Grade Antigen Purified Human Cord Serum N/A EIA,WB MG A01406H View SDS View COA Order A Sample
MAb to Human Alpha Fetoprotein Monoclonal Purified Mouse IgG1 EIA,Pr MG M86641M View SDS View COA Order A Sample
MAb to AFP Receptor Monoclonal Purified Mouse IgG2a ICC,WB,Blo MG M86501M View SDS View COA Order A Sample
MAb to Human Alpha Fetoprotein Monoclonal Purified Mouse IgG2a EIA,Pr MG M86304M View SDS View COA Order A Sample
MAb to Human Alpha Fetoprotein Monoclonal Purified Mouse IgG2a EIA,LF MG M01255M View SDS View COA Order A Sample
MAb to Human Alpha Fetoprotein Monoclonal Purified Mouse IgG1,k EIA MG M01254M View SDS View COA Order A Sample
MAb to Alpha Fetoprotein (AFP) Monoclonal Purified Mouse IgG1,k EIA,Pr MG MAM01-301 View SDS View COA Order A Sample
MAb to Alpha Fetoprotein (AFP) Monoclonal Purified Mouse IgG2b,k EIA,IHC,Pr MG MAM01-210 View SDS View COA Order A Sample
MAb to Human Alpha Fetoprotein Monoclonal Purified Mouse IgG1 EIA,RIA MG H45610M View SDS View COA Order A Sample
MAb to Human Alpha Fetoprotein Monoclonal Purified Mouse IgG1 EIA,Pr,RIA MG H45301M View SDS View COA Order A Sample

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