PIVKA
Protein Induced by Vitamin K Absence or antagonist-II (PIVKA-II) or des-gamma-carboxy prothrombin (DCP) is the precursor and abnormal form of prothrombin which was originally found in patients with hepatocellular carcinoma (HCC). PIVKA-II is thought to be produced as a consequence of an acquired defect of post-translational carboxylation of prothrombin’s precursor. In conjunction with alpha-fetoprotein (AFP), PIVKA-II is used to diagnose and manage HCC. Overall, assays detecting both PIVKA-II and AFP have shown a sensitivity and specificity of 94% and 98.5%, respectively.
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| Name | Type | Format | Host/Source | Isotype | Tested Apps | Unit | Catalog | SDS | COA | Request Sample |
|---|---|---|---|---|---|---|---|---|---|---|
| MAb to PIVKA-II | Monoclonal | Purified | Mouse | IgG1 | EIA,Pr | MG | M01344M | SDSSafety Data Sheet | COACERTIFICATE OF ANALYSIS | Request Sample |
| MAb to PIVKA-II | Monoclonal | Purified | Mouse | IgG1 | EIA,Pr | MG | M01343M | SDSSafety Data Sheet | COACERTIFICATE OF ANALYSIS | Request Sample |
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