PIVKA
Protein Induced by Vitamin K Absence or antagonist-II (PIVKA-II) or des-gamma-carboxy prothrombin (DCP) is the precursor and abnormal form of prothrombin which was originally found in patients with hepatocellular carcinoma (HCC). PIVKA-II is thought to be produced as a consequence of an acquired defect of post-translational carboxylation of prothrombin’s precursor. In conjunction with alpha-fetoprotein (AFP), PIVKA-II is used to diagnose and manage HCC. Overall, assays detecting both PIVKA-II and AFP have shown a sensitivity and specificity of 94% and 98.5%, respectively.
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PIVKA Products (2)
| Name | Type | Format | Host/Source | Isotype | Tested Apps | Unit | Catalog | Buffer | Immunogen | Recombinant | Description | Notes | SDS | COA | New Product | Recommended Product | Order a Sample | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MAb to PIVKA-II | Monoclonal | Purified | Mouse | IgG1 | EIA,Pr | MG | M01343M | No | View SDS | View COA | 0 | 0 | Order a Sample | ||||||
| MAb to PIVKA-II | Monoclonal | Purified | Mouse | IgG1 | EIA,Pr | MG | M01344M | No | View SDS | View COA | 0 | 0 | Order a Sample |
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