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Lipoprotein-Associated Phospholipase A2 (Lp-PLA2)

Lipoprotein-associated phospholipase A2 (Lp-PLA2) is an inflammatory enzyme primarily produced by lymphocytes and macrophages. In plasma, Lp-PLA2 is predominantly bound to LDL and preferentially cleaves oxidized phospholipids, resulting in the generation of lysophosphatidylcholine and oxidized FFAs, both of which are proatherogenic and contribute to the cytotoxic effects of oxidized LDL on macrophages. Elevated levels of Lp-PLA2 indicate a greater risk of plaque formation and rupture and can indicate an increased risk of cardiac events. Approximately two-thirds of heart attacks and strokes are caused by the rupture of an unstable, rupture-prone atherosclerotic plaque.

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Clear Results
5 Results
Name
Type
Format
Host/Source
Isotype
Tested Apps
Unit
Catalog
SDS
COA
Request Sample
LP-PLA2, Recombinant
Antigen
Purified
E. coli
N/A
N/A
MG
A01413H
MAb to Lp-PLA2
Monoclonal
Purified
Mouse
IgG1
EIA, Pr
MG
H01389M
MAb to Lp-PLA2
Monoclonal
Purified
Mouse
IgG1
EIA, Pr
MG
H01390M
MAb to Lp-PLA2
Monoclonal
Purified
Mouse
IgG1
EIA, Pr
MG
H01392M
MAb to Lp-PLA2
Monoclonal
Purified
Mouse
IgG1
EIA, Pr
MG
H01393M

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