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Cortisol

Cortisol is the primary glucocorticoid secreted by the adrenal gland in response to ACTH stimulation, stress, or low blood-glucose concentration. It functions to increase blood sugar through gluconeogenesis, to suppress the immune system, and to aid in the metabolism of fat, protein, and carbohydrates. It also decreases bone formation. It is secreted in a diurnal pattern with levels rising in the early morning, peaking around 8 am, and flattening in the evening.

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Cortisol Products (6)

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Name Type Format Host/Source Isotype Tested Apps Unit Catalog Buffer Immunogen Recombinant Description Notes SDS COA New Product Recommended Product Order a Sample
MAb to Cortisol Monoclonal Purified Mouse IgG1,k EIA,LF,WB MG MAS01-501 No View SDS View COA 0 Order a Sample
MAb to Cotinine Monoclonal Purified Mouse IgG1 EIA MG G01257M No View SDS View COA 0 Order a Sample
MAb to Cortisol Monoclonal Purified Mouse IgG1 EIA MG E86322M No View SDS View COA 0 Order a Sample
MAb to Cortisol Monoclonal Purified Mouse IgG3 EIA MG E86232M No View SDS View COA 0 Order a Sample
MAb to Cortisol Monoclonal Purified Mouse IgG EIA,Pr MG E82294M No View SDS View COA 0 Order a Sample
MAb to Cortisol Monoclonal Purified Mouse IgG2a EIA MG E01332M No View SDS View COA 0 Order a Sample

Cortisol

The production of too much cortisol can cause Cushing’s syndrome which, if left untreated, can lead to serious health problems such as heart attack, stroke, blood clots and Type 2 diabetes. The most common cause of Cushing’s syndrome is the long-term, high-dose use of the cortisol-like glucocorticoids which are used to treat other medical conditions like asthma, rheumatoid arthritis, and lupus. The second most common cause is pituitary tumors or a tumor on the adrenal gland itself. Too little cortisol can be caused by Addison’s disease (also called primary adrenal insufficiency), a condition in which your adrenal glands do not function well due to autoimmune disorders, tumors, or infections like tuberculosis or HIV.

Diagnosis

Cortisol disorders are generally diagnosed using competitive quantitative immunoassays from urine, saliva, or blood samples.

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