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Insulin

Insulin is a peptide hormone secreted by the β cells of the pancreatic islets of Langerhans and maintains normal blood glucose levels by facilitating cellular glucose uptake, regulating carbohydrate, lipid and protein metabolism and promoting cell division and growth through its mitogenic effects. C-peptide is a byproduct created when insulin is produced. Both insulin and C-peptide are created from a larger molecule called proinsulin which undergoes enzymatic cleavage to become des-31,32-proinsulin and des-64,65-proinsulin and eventually, insulin and C-peptide (an inactive peptide chain).

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Insulin Products (9)

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Name Type Format Host/Source Isotype Tested Apps Unit Catalog SDS COA Request Sample
MAb to Insulin Monoclonal HRP Mouse IgG1,k N/A MG E86802P View SDS View COA Order A Sample
MAb to Insulin Monoclonal Purified Mouse IgG1,k EIA MG E86705M View SDS View COA Order A Sample
MAb to Insulin C-terminal Monoclonal Purified Mouse IgG1,k EIA MG E86211M View SDS View COA Order A Sample
MAb to Insulin/proinsulin, Rat Monoclonal Purified Mouse IgG1,k EIA,IHC,Pr MG E86210M View SDS View COA Order A Sample
MAB TO INSULIN Monoclonal Purified Mouse IgG1,k EIA,IHC,Pr MG E86201M View SDS View COA Order A Sample
MAb to Insulin Monoclonal Purified Mouse IgG1,k EIA,Pr MG E86102M View SDS View COA Order A Sample
MAb to Insulin/proinsulin, Rat Monoclonal Purified Mouse IgG1 EIA,IHC,Pr MG E01346M View SDS View COA Order A Sample
MAb to Insulin/proinsulin, Rat Monoclonal Purified Mouse IgG1 EIA,IHC,Pr MG E01345M View SDS View COA Order A Sample
MAb to Insulin/proinsulin, Rat Monoclonal Biotin Mouse IgG1 EIA,IHC,Pr MG E01345B View SDS View COA Order A Sample

Diagnosis

Early assays for insulin, proinsulin, and C-peptide were competitive RIAs, however, most commercial assays are now competitive (Insulin and C-peptide) or two-site enzyme immunoassays (total or intact proinsulin).

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