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Toxoplasma gondii

Toxoplasmosis is a disease caused by the protozoan parasite Toxoplasma gondii, one of the world’s most common parasites. Infection usually occurs by eating undercooked contaminated meat, exposure from infected cat feces, or mother-to-child transmission during pregnancy. The disease can cause flu-like symptoms but in general, infected people are asymptomatic. Infants born to infected mothers and for people with weakened immune systems, toxoplasmosis can cause serious complications.

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18 Results
Name
Type
Format
Host/Source
Isotype
Tested Apps
Unit
Catalog
SDS
COA
Request Sample
toxoplasma gondii P29(gra7)
Antigen
Purified
E. coli
N/A
N/A
MG
R01803
Chimtoxo1, Recombinant
Antigen
Purified, Liquid
Pichia pastoris
N/A
EIA
MG
R01794
toxoplasma gondii antigen
Antigen
Purified
Vero Cells
N/A
EIA, WB
ML
8200
toxoplasma gondii antigen(IgM)
Antigen
Purified
Vero Cells
N/A
EIA, WB
MG
8159
T. gondii antigen (RH), Conc.
Antigen
Purified
Vero Cells
N/A
EIA, WB
MG
8158
MAb to toxoplasma gondii
Monoclonal
HRP
Mouse
IgG2a
EIA, IFA, WB
MG
C86319P
toxo gondii Sag1 (p30), Recomb
Antigen
Purified
E. coli
N/A
EIA, WB
MG
R01573
toxo gondii P35 (GRA8), Recomb
Antigen
Purified
E. coli
N/A
EIA, WB
MG
R01581
MAb to toxoplasma gondii
Monoclonal
Purified
Mouse
IgG2
EIA, IB, IFA
MG
C65620M
toxoplasma gondii MIC 3 Recomb
Antigen
Purified
E. coli
N/A
EIA, WB
MG
R18612
MAb to toxoplasma gondii MIC3
Monoclonal
Purified
Mouse
IgG1
EIA, IFA, WB
MG
C01587M
MAb to toxoplasma gondii SAG1
Monoclonal
Purified
Mouse
IgG2a
EIA, IFA, WB
MG
C01523M
Toxoplasma gondii P24 (GRA1)
Antigen
Purified
E. coli
N/A
EIA, WB
MG
R18262
Toxoplasma gondii P29 (GRA7)
Antigen
Purified
E. coli
N/A
EIA, WB
MG
R18306
MAb to toxoplasma gondii
Monoclonal
Purified
Mouse
IgG1
EIA, IFA, WB
MG
C01589M
Rabbit anti toxoplasma gondii
Polyclonal
Purified
Rabbit
N/A
EIA, IFA
ML
B01438R
MAb to toxoplasma gondii
Monoclonal
Purified
Mouse
IgG2a
EIA, IFA, WB
MG
C86319M
T. gondii P30 (SAG1) Recomb.
Antigen
Purified
E. coli
N/A
EIA, WB
MG
R18426

Toxoplasma gondii

The only known definitive hosts for Toxoplasma gondii are members of family Felidae (domestic cats and their relatives). Unsporulated oocysts are shed in the cat’s feces and these take 1-5 days to sporulate in the environment and become infectious. Intermediate hosts in nature (including birds and rodents) become infected after ingesting soil, water, or plant material contaminated with oocysts. Cats become infected after consuming intermediate hosts harboring tissue cysts. Humans can become infected by any of the following routes:

  • Eating undercooked meat of animals harboring tissue cysts
  • Consuming food or water contaminated with cat feces or by contaminated environmental samples (such as fecal contaminated soil or changing the litter box of a pet cat)
  • Blood transfusion or organ transplantation
  • Transplacentally from mother to fetus

Congenital toxoplasmosis is a group of symptoms that occur when a fetus is infected with T. gondii. If a mother becomes infected while pregnant, the parasite can spread to a developing fetus across the placenta. The risk of congenital disease is lowest (10 – 25%) when maternal infection occurs during the first trimester and highest (60 – 90%) when maternal infection occurs during the third trimester. Congenital disease is most severe when infection is acquired in the first trimester. The overall risk of congenital infection from acute T. gondii infection during pregnancy ranges from approximately 20 – 50%.

Diagnosis

Diagnosis of toxoplasmosis is usually made by detection of Toxo-specific IgG and IgM antibodies. A test that only measures IgG is used to determine if a person has previously been infected. When it is necessary to try to estimate the time of infection, such as in pregnancy, an IgM test is also used along with other tests such as an IgG avidity test. Diagnosis can also be made by direct observation of the parasite in stained tissue sections, cerebrospinal fluid (CSF), or other biopsy material.

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