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Toxoplasma gondii

Toxoplasmosis is a disease caused by the protozoan parasite Toxoplasma gondii, one of the world’s most common parasites. Infection usually occurs by eating undercooked contaminated meat, exposure from infected cat feces, or mother-to-child transmission during pregnancy. The disease can cause flu-like symptoms but in general, infected people are asymptomatic. Infants born to infected mothers and for people with weakened immune systems, toxoplasmosis can cause serious complications.

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Toxoplasma gondii Products (19)

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Name Type Format Host/Source Isotype Tested Apps Unit Catalog Buffer Immunogen Recombinant Description Notes SDS COA New Product Recommended Product Order a Sample
Rabbit anti toxoplasma gondii Polyclonal Purified Rabbit N/A EIA,IFA ML B01438R No View SDS View COA 0 Order a Sample
Toxoplasma gondii Ag (RH88) Antigen N/A Vero Cells - LF,EIA,WB,CLI ML BN1220 No View COA 0 Order a Sample
toxoplasma gondii antigen Antigen Purified Vero Cells N/A EIA,WB ML 8200 No View SDS View COA 0 Order a Sample
T. gondii SAG1/p30, Rec. Antigen Aff.Pur. Human whole cell culture N/A EIA,WB,CLI MG 8160 No View SDS View COA 0 Order a Sample
toxoplasma gondii antigen(IgM) Antigen Purified Vero Cells N/A EIA,WB MG 8159 No View SDS View COA 0 Order a Sample
T. gondii antigen (RH), Conc. Antigen Purified Vero Cells N/A EIA,WB MG 8158 No View SDS View COA 0 Order a Sample
T. gondii P30 (SAG1) Recomb. Antigen Purified E. coli N/A EIA,WB MG R18426 No View SDS View COA 0 Order a Sample
Toxoplasma gondii P29 (GRA7) Antigen Purified E. coli N/A EIA,WB MG R18306 No View SDS View COA 0 Order a Sample
toxoplasma gondii P29(gra7) Antigen Purified E. coli N/A EIA,LF,WB,CLI MG R01803 No View SDS View COA 0 Order a Sample
toxo Gondi P30 (sag 1) Recomb Antigen Purified Pichia pastoris N/A EIA,WB MG R01797 No View SDS View COA 0 Order a Sample
Chimtoxo1, Recombinant Antigen Purified, Liquid Pichia pastoris N/A EIA,WB MG R01794 No View SDS View COA 0 Order a Sample
toxo gondii P35 (GRA8), Recomb Antigen Purified E. coli N/A EIA,WB MG R01581 No View SDS View COA 0 Order a Sample
toxo gondii Sag1 (p30), Recomb Antigen Purified E. coli N/A EIA,WB MG R01573 No View SDS View COA 0 Order a Sample
MAb to toxoplasma gondii Monoclonal HRP Mouse IgG2a EIA,WB,IFA MG C86319P No View SDS View COA 0 Order a Sample
MAb to toxoplasma gondii Monoclonal Purified Mouse IgG2a EIA,IFA,WB MG C86319M No View SDS View COA 0 Order a Sample
MAb to toxoplasma gondii Monoclonal Purified Mouse IgG2 EIA,IFA,IB MG C65620M No View SDS View COA 0 Order a Sample
MAb to toxoplasma gondii Monoclonal Purified Mouse IgG1 EIA,IFA,WB MG C01589M No View SDS View COA 0 Order a Sample
MAb to toxoplasma gondii MIC3 Monoclonal Purified Mouse IgG1 EIA,IFA,WB MG C01587M No View SDS View COA 0 Order a Sample
MAb to toxoplasma gondii SAG1 Monoclonal Purified Mouse IgG2a EIA,IFA,WB MG C01523M No View SDS View COA 0 Order a Sample

Toxoplasma gondii

The only known definitive hosts for Toxoplasma gondii are members of family Felidae (domestic cats and their relatives). Unsporulated oocysts are shed in the cat’s feces and these take 1-5 days to sporulate in the environment and become infectious. Intermediate hosts in nature (including birds and rodents) become infected after ingesting soil, water, or plant material contaminated with oocysts. Cats become infected after consuming intermediate hosts harboring tissue cysts. Humans can become infected by any of the following routes:

  • Eating undercooked meat of animals harboring tissue cysts
  • Consuming food or water contaminated with cat feces or by contaminated environmental samples (such as fecal contaminated soil or changing the litter box of a pet cat)
  • Blood transfusion or organ transplantation
  • Transplacentally from mother to fetus

Congenital toxoplasmosis is a group of symptoms that occur when a fetus is infected with T. gondii. If a mother becomes infected while pregnant, the parasite can spread to a developing fetus across the placenta. The risk of congenital disease is lowest (10 – 25%) when maternal infection occurs during the first trimester and highest (60 – 90%) when maternal infection occurs during the third trimester. Congenital disease is most severe when infection is acquired in the first trimester. The overall risk of congenital infection from acute T. gondii infection during pregnancy ranges from approximately 20 – 50%.

Diagnosis

Diagnosis of toxoplasmosis is usually made by detection of Toxo-specific IgG and IgM antibodies. A test that only measures IgG is used to determine if a person has previously been infected. When it is necessary to try to estimate the time of infection, such as in pregnancy, an IgM test is also used along with other tests such as an IgG avidity test. Diagnosis can also be made by direct observation of the parasite in stained tissue sections, cerebrospinal fluid (CSF), or other biopsy material.

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