Apolipoprotein
Apolipoproteins are lipid transport proteins, helping to move lipids (and fat-soluble vitamins) in the body. They are produced in the small intestine and the liver and each apolipoprotein have a specific function in lipid transport and metabolism. Apolipoprotein A (Apo A) is the primary portion of the high-density lipoprotein (HDL) which plays an important role in transporting cholesterol from the peripheral tissues to the liver, where it can be excreted. Apo B, specifically the form ApoB-100, is the main lipoprotein of low-density lipoprotein (LDL) and which are the primary driver of plaques that cause vascular disease. Apo E is a major component of HDL-like particles in the brain and high levels are associated with increased all-cause, cardiovascular, and cancer mortality. The ε4 allele of Apo E is also the major genetic risk factor for Alzheimer's disease. Diagnostic assays that measure the levels of Apo B-100 help determine the risk of developing cardiovascular disease and sometimes help monitor treatment for high cholesterol. Apo A testing is typically done in combination with Apo B as apo B/apo A1 ratio has been shown to be predictive of ischemic stroke in patients. Apo E levels are measured for diagnosing hyperlipoproteinemia in patients with increase plasma triglycerides and cholesterol.
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Name | Type | Format | Host/Source | Isotype | Tested Apps | Unit | Catalog | SDS | COA | Request Sample |
---|---|---|---|---|---|---|---|---|---|---|
MAb to Apolipoprotein B | Monoclonal | Purified | Mouse | IgG2b,k | EIA,LF,WB | MG | MAC23-035 | COA | Request Sample | |
MAb to Apolipoprotein B | Monoclonal | Purified | Mouse | IgG2b | RIA | MG | MAC23-031 | COA | Request Sample | |
MAb to Apolipoprotein AI | Monoclonal | Purified | Mouse | IgG2a,k | RIA | MG | MAC20-029 | COA | Request Sample | |
MAb to Apolipoprotein AI | Monoclonal | Purified | Mouse | IgG2a,k | RIA | MG | MAC20-001 | COA | Request Sample | |
Rabbit anti Human Apo CIII | Polyclonal | Aff.Pur. | Rabbit | N/A | EIA,IB | MG | K97113R | SDS | COA | Request Sample |
Rabbit anti Human Apo CII | Polyclonal | Aff.Pur. | Rabbit | N/A | EIA,IB | MG | K97112R | COA | Request Sample | |
Sheep anti Human Apo (a) | Polyclonal | Aff.Pur. | Sheep | N/A | EIA,WB | MG | K97110S | COA | Request Sample | |
Goat anti Apo E | Polyclonal | Aff.Pur. | Goat | N/A | EIA,WB | MG | K74190G | COA | Request Sample | |
Goat anti Apo E | Polyclonal | Biotin | Goat | N/A | EIA,WB | ML | K74180B | SDS | COA | Request Sample |
Goat anti Apo B | Polyclonal | Monospecific | Goat | N/A | IEP,TIA | ML | K62200G | COA | Request Sample | |
Goat anti Mouse Apo AI | Polyclonal | Neat | Goat | N/A | RIA | ML | K23600G | COA | Request Sample | |
Rabbit anti-mouse Apo B48/100 | Polyclonal | Neat | Rabbit | N/A | WB | ML | K23300R | SDS | COA | Request Sample |
Rabbit anti Apo AI, Mouse | Polyclonal | Aff.Pur. | Rabbit | N/A | EIA,RID,WB | MG | K23001R | COA | Request Sample | |
Goat anti Apo B | Polyclonal | Monospecific | Goat | N/A | IEP | ML | K04323G | SDS | COA | Request Sample |
MAb to Human Apo E | Monoclonal | Purified | Mouse | IgG1 | EIA,IHC,WB | ML | H61529M | COA | Request Sample | |
MAb to Apolipoprotein AI | Monoclonal | Purified | Mouse | IgG1 | EIA,RIA | MG | H45625M | SDS | COA | Request Sample |
MAb to Apolipoprotein AI | Monoclonal | Purified | Mouse | IgG1 | EIA,RIA | MG | H45404M | COA | Request Sample | |
MAb to Apolipoprotein AI | Monoclonal | Purified | Mouse | IgG1 | EIA,RIA | MG | H45402M | Request Sample | ||
MAb to Human Apolipoprotein B | Monoclonal | Purified | Mouse | IgG2b | EIA,RIA | MG | H45160M | COA | Request Sample | |
Goat anti Apolipoprotein E | Polyclonal | Aff.Pur. | Goat | N/A | N/A | MG | G5C27-766 | SDS | COA | Request Sample |
Goat anti Apolipoprotein AII | Polyclonal | Aff.Pur. | Goat | N/A | IEP | MG | G5C21-766 | COA | Request Sample | |
Goat anti Apolipoprotein AI | Polyclonal | Aff.Pur. | Goat | N/A | IEP | MG | G5C20-766 | COA | Request Sample | |
Human Apolipoprotein AI | Antigen | Purified | Human Plasma HDL | N/A | N/A | MG | A95120H | SDS | COA | Request Sample |
Apo AI/B Calibrator 3 | Antigen | Purified | Human Plasma | N/A | TIA | ML | A62934H | SDS | COA | Request Sample |
Human Apo B-100 | Antigen | Purified | Human Plasma | N/A | N/A | MG | A34300H | COA | Request Sample | |
Human Beta-2 gp I, Apo H | Antigen | Purified | Human Plasma | N/A | EIA | MG | A3C083H | SDS | COA | Request Sample |