RSV

Respiratory Syncytial Virus (RSV) is a common respiratory virus that usually causes mild, cold-like symptoms but can cause more serious problems such as bronchiolitis and pneumonia in babies and young children. In the United States, 60% of infants are infected during their first RSV season, and nearly all children will have been infected with the virus by 2–3 years of age.

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Name	Type	Format	Host/Source	Isotype	Tested Apps	Unit	Catalog	SDS	COA	Request Sample
Inactivated RSV antigen	Antigen	Purified, Liquid	Mammalian Cells	N/A	EIA,LF,WB,CLI	MG	9596	SDS	COA	Request Sample
Inactivated RSV antigen	Antigen	Lysate	HEp-2	N/A	EIA	MG	9592	SDS	COA	Request Sample
MAb to RSV	Monoclonal	Purified, Liquid	Mouse	IgG1	EIA,LF	MG	9584		COA	Request Sample
MAb to RSV	Monoclonal	Purified, Liquid	Mouse	IgG1	EIA,LF,Pr	MG	9583		COA	Request Sample
RSV Grade II antigen	Antigen	Partially Purified	FRhK Cells	N/A	EIA	ML	8175	SDS	COA	Request Sample
RSV, Long Strain	Antigen	Purified	MA104 Cells	N/A	EIA	MG	R86900	SDS	COA	Request Sample
RSV Long Strain	Antigen	Purified	Vero Cells	N/A	EIA	MG	R01714	SDS	COA	Request Sample
MAb to RSV, Long Strain	Monoclonal	Purified	Mouse	IgG2a	EIA,LF	MG	C86001M	SDS	COA	Request Sample
MAb to RSV	Monoclonal	Purified	Mouse	IgG	DB,LF	MG	C66432M	SDS	COA	Request Sample
MAb to RSV	Monoclonal	Purified	Mouse	IgG2b	EIA,IFA	MG	C65816M		COA	Request Sample
MAb to RSV	Monoclonal	Purified	Mouse	IgG2a	EIA,IFA	MG	C65067M		COA	Request Sample
MAb to RSV	Monoclonal	FITC	Mouse	IgG2a	EIA,IFA	MG	C65067F		COA	Request Sample
MAb to RSV Fusion Protein	Monoclonal	Purified	Mouse	IgG2a	EIA,IFA,Neu,Pr,LF	MG	C65065M	SDS	COA	Request Sample
MAb to RSV Fusion Protein	Monoclonal	Purified	Mouse	IgG1	EIA,IFA,Neu,Pr,LF	MG	C65064M	SDS	COA	Request Sample
MAb to RSV	Monoclonal	Purified	Mouse	IgG2a	EIA,IFA,Pr,LF	MG	C65063M	SDS	COA	Request Sample
MAb to RSV Fusion Protein	Monoclonal	Purified	Mouse	IgG2a	EIA	MG	C01777M	SDS	COA	Request Sample
MAb to RSV Fusion Protein	Monoclonal	Purified	Mouse	IgG1	EIA,Pr,LF	MG	C01776M	SDS	COA	Request Sample
MAb to RSV Fusion Protein	Monoclonal	Purified	Mouse	IgG2a	EIA,Pr	MG	C01775M	SDS	COA	Request Sample
MAb to RSV Fusion Protein	Monoclonal	Purified	Mouse	IgG2a	EIA,Pr	MG	C01774M	SDS	COA	Request Sample
MAb to RSV Fusion Protein	Monoclonal	Purified	Mouse	IgG1	EIA,Pr	MG	C01773M	SDS	COA	Request Sample
MAb to RSV Fusion Protein	Monoclonal	Purified	Mouse	IgG1	EIA	MG	C01772M	SDS	COA	Request Sample
MAb to RSV Fusion Protein	Monoclonal	Purified	Mouse	IgG2a	EIA	MG	C01771M	SDS	COA	Request Sample
MAb to RSV Fusion Protein	Monoclonal	Purified	Mouse	IgG2a	EIA,Pr	MG	C01770M	SDS	COA	Request Sample
MAb to RSV Fusion Protein	Monoclonal	Purified	Mouse	IgG2b	EIA,Pr	MG	C01769M	SDS	COA	Request Sample
MAb to RSV, Long Strain	Monoclonal	Purified	Mouse	IgG2b	EIA,LF	MG	C01694M		COA	Request Sample
MAb to RSV Fusion Protein	Monoclonal	Purified	Mouse	IgG2a,k	EIA,FC,IFA,WB	MG	C01626M	SDS	COA	Request Sample
MAb to RSV Nucleoprotein	Monoclonal	Purified	Mouse	IgG1	EIA,LF,WB	MG	C01287M	SDS	COA	Request Sample
MAb to RSV Fusion Protein	Monoclonal	Purified	Mouse	IgG2b	EIA,LF,WB	MG	C01286M		COA	Request Sample
Goat anti RSV (all antigens)	Polyclonal	Purified	Goat	N/A	EIA,IFA,IHC	ML	B65860G	SDS	COA	Request Sample
Goat anti RSV	Polyclonal	HRP	Goat	N/A	EIA,IHC,Neu,ICC,WB	ML	B65840G	SDS	COA	Request Sample
Goat anti-RSV	Polyclonal	FITC	Goat	N/A	EIA,IHC,FC,WB	ML	B65830G	SDS	COA	Request Sample
Goat anti-RSV	Polyclonal	Biotin	Goat	N/A	EIA,IFA,IHC,Neu	ML	B65820G		COA	Request Sample

Respiratory Syncytial Virus (RSV)

RSV is single-stranded RNA virus of the family Paramyxoviridae, which includes common respiratory viruses such as measles and mumps. It spreads from direct and indirect contact with nasal or oral secretions from infected people. The virus can survive on hard surfaces such as tables and crib rails for many hours, and on soft surfaces such as tissues and hands for shorter amounts of time.

Symptoms usually appear within 4 to 6 days of infection and healthy individuals usually recover within 1-2 weeks. When infants and children are exposed to RSV for the first time:

25-40% will have signs or symptoms of bronchiolitis or pneumonia
5 to 20 out of 1,000 will require hospitalization (most children hospitalized for RSV infection are younger than 6 months of age)

Researchers are developing an RSV vaccine, but none is available yet. There is no specific treatment for RSV.

Diagnosis

Several different types of laboratory tests are available for the diagnosis of RSV infection including ELISA, rapid lateral flow, direct fluorescent antibody detection (DFA), neutralization assay and RT-PCR. Most clinical laboratories currently utilize EIA antigen detection tests, and many supplement antigen testing with cell culture or immunofluorescence assays to confirm diagnosis. Two viral proteins, the attachment glycoprotein G and the surface glycoprotein F, are the main antigens responsible for inducing a neutralizing immune response and resistance to infection.

Antigen detection tests and culture are generally reliable in young children but less useful in older children and adults. Because of its thermolability, the sensitivity of RSV isolation in cell culture from respiratory secretions can vary among laboratories. IgG and IgM antibody tests are used less frequently for routine diagnosis. Although useful for seroprevalence and epidemiologic studies, a diagnosis using paired acute- and convalescent-phase sera to demonstrate a significant rise in antibody titer to RSV cannot be made in time to guide patient care.

Respiratory Diseases

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RSV