Next-Generation Sequencing
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Library mapping efficiency and comparable GC content after lyophilization
| Library | Average mapped reads (%) |
|---|---|
| Lyophilized reagents | 99.79 ± 0.04 |
| Liquid reagents | 99.79 ± 0.12 |
Meridian's NGS Products
Glycerol-Free NGS Library Prep Enzymes
Meridian is the sole provider of the most extensive array of glycerol-free NGS enzymes essential for enabling the preparation of sequencing kits that can be shipped and stored at ambient temperature.
NGS Library Preparation Kit
Meridian’s Lyophilized NGS Library Preparation Kit is designed for next-generation sequencing (NGS) and is optimized for SBS protocols. This kit is lyophilized, making it stable for shipment and storage at room temperature for up to 12 months, ensuring consistent performance and convenience.
Supporting Products:
In addition to the glycerol-free enzymes; Meridian also offers a comprehensive list of supporting products to enable a complete sequencing kit solution.
Product Description & Applications
Meridian’s glycerol-free NGS Library Prep Enzymes enable high-fidelity, high-efficiency library preparation, allowing sequencing kits to be shipped and stored at ambient temperature for greater accessibility. Ambient-temperature NGS assays eliminate cold-chain logistics, expanding access to genomic testing in resource-limited settings. By driving scalable, high-performance sequencing technologies, Meridian is bridging the gap, making NGS-based diagnostics more accessible, efficient, and impactful worldwide.
Next-generation sequencing (NGS) is widely used in clinical diagnostics and precision medicine, with applications spanning oncology, infectious disease, reproductive health, and genetic disorder screening. In cancer care, NGS supports companion diagnostics (CDx) for targeted therapies, minimal residual disease (MRD) monitoring, and liquid biopsy for non-invasive tumor detection. It plays a crucial role in infectious disease diagnostics, identifying pathogens, antimicrobial resistance markers, and tracking viral outbreaks. In reproductive medicine, NGS enables non-invasive prenatal testing (NIPT), carrier screening, and preimplantation genetic testing (PGT). Additionally, it is instrumental in rare disease diagnosis, pharmacogenomics, transplant medicine, and neurological disorder screening, offering personalized insights for treatment decisions. As NGS technology advances, its role in cardiovascular risk assessment, immunogenetics, and population genomics continues to expand, further integrating precision medicine into routine clinical practice.
Catalogs & Brochures
Next-Generation Sequencing (NGS)Next-Generation Sequencing (NGS)Catalog
Check out our NGS-Related Blog Articles
Here are some recent blog articles about Next-Generation Sequencing (NGS):
References:
Zalis, M., Viana Veloso, G. G., Aguiar Jr., P. N., Gimenes, N., Reis, M. X., Matsas, S., & Ferreira, C. G. (2024). Next-generation sequencing impact on cancer care: Applications, challenges, and future directions. Frontiers in Genetics, 15, 1420190. https://doi.org/10.3389/fgene.2024.1420190
Meric-Bernstam, F., Brusco, L., Daniels, M., Wathoo, C., Bailey, A. M., Strong, L., & Shaw, K. (2019). Clinical applications of next-generation sequencing in precision oncology. NPJ Precision Oncology, 3, 4. https://doi.org/10.1038/s41698-019-0073-4
To detect more alterations, consider adding companion testing to NGS. (n.d.). Targeted Oncology. Retrieved from https://www.targetedonc.com/view/to-detect-more-alterations-consider-adding-companion-testing-to-ngs