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Adenovirus

Adenoviruses are a family of DNA viruses that are an important cause of febrile illnesses in young children. They are most frequently associated with upper respiratory tract syndromes such as pharyngitis but can also cause pneumonia and less commonly, gastrointestinal, ophthalmologic, genitourinary, neurologic, and disseminated disease. Most adenoviral diseases are self-limiting, although fatal infections can occur in immunocompromised patients and occasionally in healthy children and adults.

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Name Type Format Host/Source Isotype Tested Apps Unit Catalog SDS COA Request Sample
Adenovirus antigen, Recomb. Antigen Purified, Liquid Mammalian Cells N/A EIA,LF,WB,CLI MG 9595 SDS COA Request Sample
MAb Adenovirus Monoclonal Purified, Liquid Mouse IgG1 EIA,Pr,LF MG 9590 SDS COA Request Sample
Adenovirus Type 6(Strain tonsi Antigen Purified Hela Cells N/A EIA MG R86310 SDS COA Request Sample
Adenovirus Type 2(adenoid 6) Antigen Purified HEp-2 N/A EIA MG R14800 SDS COA Request Sample
Adenovirus (Strain Adenoid 6) Antigen Lysate MRC-5 Cells N/A EIA ML R02721 SDS COA Request Sample
MAb to Adenovirus Hexon Monoclonal Purified Mouse IgG2a EIA,Pr,ID,IHC MG C86804M SDS COA Request Sample
MAb to Adenovirus Hexon Monoclonal Purified Mouse Mixed EIA,Pr,ID MG C86007M SDS COA Request Sample
MAb to Adenovirus Hexon Monoclonal Purified Mouse Mixed EIA,LF,Pr MG C86006M SDS COA Request Sample
MAb to Adenovirus Monoclonal Purified Mouse IgG EIA MG C66440M SDS COA Request Sample
MAb to Adenovirus Monoclonal Purified Mouse IgG EIA MG C66439M SDS COA Request Sample
MAb to Adenovirus Monoclonal Purified Mouse IgG EIA,LF,WB MG C66437M SDS COA Request Sample
MAb to Adenovirus 40 & 41 Monoclonal Purified Mouse IgG2a EIA,ST MG C66431M SDS COA Request Sample
MAb to Adenovirus Hexon Monoclonal Purified Mouse IgG1 EIA,IFA,LF,Pr,ST MG C65604M SDS COA Request Sample
MAb to Bordetella Pertussis Monoclonal Purified Mouse IgG3 EIA,IFA,WB MG C65500M SDS COA Request Sample
MAb to Adenovirus Monoclonal FITC Mouse IgG1 EIA,IFA ML C65433F SDS COA Request Sample
MAb to Adenovirus Monoclonal Purified Mouse IgG1 EIA,IFA,LF,Pr,ST MG C65431M SDS COA Request Sample
MAb to Adenovirus Hexon Monoclonal FITC Mouse IgG1 EIA,IFA MG C65136M SDS COA Request Sample
MAb to Adenovirus Monoclonal Purified Mouse IgG EIA,LF,ST MG C11994M SDS COA Request Sample
MAb to Adenovirus Hexon Monoclonal Purified Mouse IgG2a LF,Pr MG C01960M COA Request Sample
MAb to Adenovirus Hexon Monoclonal Purified Mouse IgG1 LF,Pr MG C01959M SDS COA Request Sample
MAb to Adenovirus Hexon Monoclonal Purified Mouse IgG2a LF,Pr,ST MG C01953M SDS COA Request Sample
MAb to Adenovirus Hexon Monoclonal Purified Mouse IgG1 EIA MG C01849M SDS COA Request Sample
MAb to Adenovirus Hexon Monoclonal Purified Mouse IgG2a EIA,Pr MG C01832M SDS COA Request Sample
MAb to Adenovirus Hexon Monoclonal Purified Mouse IgG2a EIA,Pr MG C01831M SDS COA Request Sample
MAb to Adenovirus Hexon Monoclonal Purified Mouse IgG2b EIA,Pr MG C01830M SDS COA Request Sample
MAb to Adenovirus Hexon Monoclonal Purified Mouse IgG1 EIA,Pr MG C01828M SDS COA Request Sample
MAb to Adenovirus Hexon Monoclonal Purified Mouse IgG2a EIA,Pr MG C01785M SDS COA Request Sample
MAb to Adenovirus Hexon Monoclonal Purified Mouse IgG1 EIA,Pr MG C01784M SDS COA Request Sample
MAb to Adenovirus Hexon Monoclonal Purified Mouse IgG2a EIA,Pr MG C01783M SDS COA Request Sample
MAb to Adenovirus Hexon Monoclonal Purified Mouse IgG2a EIA MG C01782M SDS COA Request Sample
MAb to Adenovirus Hexon Monoclonal Purified Mouse IgG2a EIA,Pr,LF MG C01781M COA Request Sample
MAb to Adenovirus Hexon Monoclonal Purified Mouse IgG2a EIA,Pr,LF MG C01780M SDS COA Request Sample
MAb to Adenovirus Hexon Monoclonal Purified Mouse IgG1 EIA MG C01779M SDS COA Request Sample
MAb to Adenovirus Hexon Monoclonal Purified Mouse IgG2a EIA MG C01778M SDS COA Request Sample
MAb to Adenovirus Hexon Monoclonal Purified Mouse IgG1 EIA,Pr,LF,ST MG C01728M SDS COA Request Sample
MAb to Adenovirus Hexon Monoclonal Purified Mouse IgG1 EIA,Pr,LF,ST MG C01727M SDS COA Request Sample
MAb to Adenovirus Hexon Monoclonal Purified Mouse IgG2a EIA,LF MG C01711M SDS COA Request Sample
MAb to Adenovirus Hexon Monoclonal Purified Mouse IgG1 EIA,LF,WB MG C01612M SDS COA Request Sample
MAb to Adenovirus Hexon Monoclonal Purified Mouse IgG1 EIA,IFA,Pr,LF,ST MG C01554M SDS COA Request Sample
MAb to Adenovirus Hexon Monoclonal Purified Mouse IgG EIA,LF,WB MG C01296M SDS COA Request Sample
MAb to Adenovirus Hexon Monoclonal Purified Mouse IgG2a EIA,IFA,LF,Pr,ST MG C01256M SDS COA Request Sample
Goat anti Adenovirus Polyclonal Purified Goat N/A EIA,IFA,WB ML B65140G SDS COA Request Sample
Goat anti Adenovirus Polyclonal FITC Goat N/A EIA,IFA,WB ML B65140F COA Request Sample
Mab to Adenovirus Monoclonal Purified, Liquid Mouse IgG1,k EIA,LF,Pr MG BN1078 SDS COA Request Sample
Mab to Adenovirus Monoclonal Purified, Liquid Mouse IgG1,k EIA,LF,Pr MG BN1077 SDS COA Request Sample

Adenovirus

Adenovirus derives its name from its initial isolation from human adenoids in 1953. To date over 50 types have been identified which are immunologically distinct. They are unusually stable to chemical or physical agents and adverse pH conditions, enabling their prolonged survival outside of the body and water. They are spread primarily via respiratory droplets, however, they can also be spread by fecal routes. Some people infected with adenoviruses can have ongoing infections in their tonsils, adenoids, and intestines that do not cause symptoms and they can shed the virus for months or years. Most infections with adenovirus result in infections of the upper respiratory tract such as conjunctivitis, tonsillitis, ear infection, or croup. Adenoviruses types 40 and 41 can also cause gastroenteritis. In babies, adenoviruses can cause coughing fits that look almost exactly like whooping cough, viral meningitis or encephalitis. Most people recover from adenovirus infections on their own, although fatal infections can occur in immunocompromised individuals.

Diagnosis

Since adenoviruses are associated with a variety of clinical symptoms and non-specific manifestations, identifying an infection based upon clinical criteria alone is challenging. Laboratory diagnosis can be made using antigen detection, PCR, virus isolation, and serology. Adenovirus typing is usually done by hemagglutination-inhibition and/or neutralization with type-specific antisera or by molecular methods. Mammalian adenoviruses share group-specific antigen epitopes (on the inside of hexons) which are the main antigens involved in the host immune response. By detecting the common hexon antigens, most commercial immunoassays are capable of recognizing the majority of Adenovirus serotypes in nasopharyngeal secretions or stool specimens. Confirmation of adenovirus infection is important in order to decide on the use of antiviral agents, exclude other treatable infections, establish a prognosis, and initiate infection control measures when appropriate.

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Have questions about a product? Want to learn more about Meridian’s molecular or immunoassay reagent portfolio? We want to hear from you!


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