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Lyo-Ready & Air-Dryable Master Mixes & Reagents

Molecular diagnostic tests are progressively moving towards lyophilized and air-dried formats. There are several advantages for this, including room temperature shipping and storage, extended shelf-life, and increased flexibility in sample volume. However, to be compatible with drying, enzyme preparations must be glycerol-free and include specialized excipients that preserve the mixture as it is exposed to various conditions, including freezing, temperature ramps, vacuum, and dehydration.
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Name Specimen Type Application Catalog Order a Sample Sizes Description Wet(Liquid) Air-Dryable Dryable Glycerol-Free Lyo-Ready Concentration High Concentration Detail Safety Data Sheet COA/Test Release User Guide Product Handling Guide
Air-Dryable Direct RNA/DNA qPCR Urine, 4x Urine, Air-Dryable Mix RT-qPCR MDX151 Order a Sample Available in 5 mL (1,000 Rxns) or 50 mL (10,000 Rxns) aliquots

Inhibitor tolerance to 20% urine. Perfect for multiplexing and fast cycling conditions. Used in the detection of urinary track infections, STD, tropical diseases, cancer screening, bladder and prostate cancer.

Yes Yes Air-Dryable Yes No 4x Yes
Air-Dryable Direct DNA qPCR Urine, 4x Urine, Air-Dryable Mix qPCR MDX150 Order a Sample Available in 5 mL (1,000 Rxns) or 50 mL (10,000 Rxns) aliquots

Inhibitor tolerance to 60% urine. Perfect for multiplexing and fast cycling conditions. Used in the detection of urinary track infections, STD, tropical diseases, cancer screening, bladder and prostate cancer.

Yes Yes Air-Dryable Yes No 4x Yes
Air-Dryable Direct RNA/DNA qPCR Stool, 4x Stool, Air-Dryable Mix RT-qPCR MDX141 Order a Sample Available in 5 mL (1,000 Rxns) or 50 mL (10,000 Rxns) aliquots

Inhibitor tolerance to 5% stool, 2 mg/mL bile salt and 40% Cary Blair media. Perfect for multiplexing and fast cycling conditions. Used in the detection of IBD, cancer, fecal microbiota and bacterial and viruses.

Yes Yes Air-Dryable Yes No 4x Yes
Air-Dryable Direct DNA qPCR Stool, 4x Stool, Air-Dryable Mix qPCR MDX140 Order a Sample Available in 5 mL (1,000 Rxns) or 50 mL (10,000 Rxns) aliquots

Inhibitor tolerance to 20% stool, 2 mg/mL bile salt and 40% Cary Blair media. Perfect for multiplexing and fast cycling conditions. Used in the detection of IBD, cancer, fecal microbiota and bacterial and viruses.

Yes Yes Air-Dryable Yes No 4x Yes
Air-Dryable Direct RNA/DNA qPCR Saliva, 4x Saliva, Sputum, Air-Dryable Mix RT-qPCR MDX131 Order a Sample Available in 5 mL (1,000 Rxns) or 50 mL (10,000 Rxns) aliquots

Inhibitor tolerance to 60% crude saliva, sputum or mucin samples and 50% UTM. Perfect for multiplexing and fast cycling conditions. Used in the detection of a broad range of diseases, including cancer, respiratory viruses and bacterial infections.

Yes Yes Air-Dryable Yes No 4x Yes
Air-Dryable Direct DNA qPCR Saliva, 4x Saliva, Sputum, Air-Dryable Mix qPCR MDX130 Order a Sample Available in 5 mL (1,000 Rxns) or 50 mL (10,000 Rxns) aliquots

Inhibitor tolerance to 60% crude saliva, sputum or mucin samples and 50% UTM. Perfect for multiplexing and fast cycling conditions. Used in the detection of a broad range of diseases, including cancer, respiratory viruses and bacterial infections.

Yes Yes Air-Dryable Yes No 4x Yes
Air-Dryable Direct DNA qPCR Plant, 4x Plant, Air-Dryable Mix qPCR MDX116 Order a Sample Available in 5 mL (1,000 Rxns) or 50 mL (10,000 Rxns) aliquots

No need for extraction, compatible with 25% Plant lysate (SDS, NaOH). Perfect for multiplexing and fast cycling conditions for in-field qPCR testing. Used for genotyping and transgene or pathogenic detection.

Yes Yes Air-Dryable Yes No 4x Yes
Air-Dryable Direct RNA/DNA qPCR Blood, 4x Blood, Plasma, Serum, Air-Dryable Mix RT-qPCR MDX121 Order a Sample Available in 5 mL (1,000 Rxns) or 50 mL (10,000 Rxns) aliquots

Inhibitor tolerance to 10% whole blood, 10% plasma, compatible with all anticoagulants. Perfect for multiplexing and fast cycling conditions. Used in the detection of blood pathogens and liquid biopsy applications.

Yes Yes Air-Dryable Yes No 4x Yes
55C MMLV-RT Reverse Transcriptase, Air-Dryable & Lyo-Ready Enzymes RT-LAMP MDX117 Order a Sample Available in 50 ‘L (10,000 Units), 200 ‘L (40,000 Units) or 1 mL (200,000 Units) aliquot

Highly robust, thermostable reverse transcriptase, ideal for cDNA synthesis from RNA with a high secondary structure such as viral RNA genomes.

Yes Requires excipients Requires excipients Yes Requires excipients 200 U/‘L Yes
Air-Dryable 1-Step RT-qPCR Mix, 4x Air-Dryable Mix RT-qPCR MDX095 Order a Sample Available in 5 mL (500 Rxns) or 50 mL (10,000 Rxns) aliquots

Glycerol-free RT-qPCR mix containing Taq polymerase, reverse transcriptase, reaction buffer, dNTPs, MgCl2 and air-dry compatible excipients, ideal for developing ambient temperature, multiplex molecular assays.

Yes Yes Air-Dryable Yes No 4x Yes
Air-Dryable Direct DNA qPCR Blood, 4x Blood, Plasma, Serum, Air-Dryable Mix qPCR MDX092 Order a Sample Available in 5 mL (1,000 Rxns) or 50 mL (10,000 Rxns) aliquots

Inhibitor tolerance to 20% whole blood, 20% plasma, compatible with all anticoagulants. Perfect for multiplexing and fast cycling conditions. Used in the detection of blood pathogens and liquid biopsy applications.

Yes Yes Air-Dryable Yes No 4x Yes
Air-Dryable qPCR Mix, 4x PCR, qPCR, Air-Dryable Mix qPCR MDX082 Order a Sample Available in 5 mL (500 Rxns) or 50 mL (10,000 Rxns) aliquots

Glycerol-free qPCR mix containing Taq polymerase, reaction buffer, dNTPs, MgCl2 and air-dry compatible excipients, ideal for developing ambient temperature, multiplex molecular assays.

Yes Yes Air-Dryable Yes No 4x Yes
Lyo-Ready qPCR Buffer w/o Excipients, 4x Buffer, Air-Dryable & Lyo-Ready Enzymes qPCR MDX061 Order a Sample Available in 2.5 mL (500 Rxns) or 100 mL (20,000 Rxns) aliquots

Glycerol-free qPCR reaction buffer that is designed to allow formulation optimization to freeze-drying methods by excipients selection.

Yes Requires excipients Air-Dryable,Lyo-Ready Yes Requires excipients 4x Yes
Lyo-Ready 1-Step RT-qPCR Buffer Buffer, Air-Dryable & Lyo-Ready Enzymes RT-qPCR MDX052 Order a Sample Available in 10 mL (1,000 Rxns) or 100 mL (10,000 Rxns) aliquots

Glycerol-free RT-qPCR reaction buffer containing lyo-excipients, designed to deliver highly reproducible, accurate RT-qPCR assay results under fast thermal cycling conditions.

Yes No Lyo-Ready Yes Yes 2x No
Lyo-Compatible MMLV-RT Reverse Transcriptase, Air-Dryable & Lyo-Ready Enzymes RT-qPCR MDX042 Order a Sample Available in 8 ‘L (1,000 Rxns) or 80 ‘L (10,000 Rxns) aliquots

Glycerol-free high concentration reverse transcriptase and dilution buffer. Can be used to create 1-step RT-qPCR mixes for subsequent lyophilization.

Yes Requires excipients Requires excipients Yes Requires excipients > 165 U/‘L Yes
Glycerol-Free Taq HS, 50 U/‘L DNA Polymerase, Air-Dryable & Lyo-Ready Enzymes PCR MDX011 Order a Sample Available in 0.02 mL (1,000 Units) or 0.5 mL (25,000 Units) aliquots

Lyophilization-compatible high-performance Taq DNA polymerase, separate Taq antibody and enzyme dilution buffer, suitable for difficult, multiplex tests that require fast amplification, whilst maintaining high specificity and sensitivity.

Yes Requires excipients Requires excipients Yes Requires excipients 50 U/mL Yes
Lyo-Ready qPCR Buffer, 2.5x Buffer, Air-Dryable & Lyo-Ready Enzymes qPCR MDX022 Order a Sample Available in 8 mL (500 Rxns) or 100 mL (12,500 Rxns) aliquots

Glycerol-free qPCR reaction buffer containing lyo-excipients, designed to deliver highly reproducible, accurate qPCR assay results under fast thermal cycling conditions.

Yes No Lyo-Ready Yes Yes 2.5x No
Aptamer Taq HS (Glycerol-Free) DNA Polymerase, Air-Dryable & Lyo-Ready Enzymes PCR MDX015 Order a Sample Available in 20 ?L (1,000 Units) or 1 mL (50,000 Units) aliquots

Glycerol-free, high concentration hot-start Taq DNA polymerase, suitable for difficult, multiplex molecular tests that require fast amplification.

Yes Requires excipients Requires excipients Yes Requires excipients 50 U/mL Yes

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Superior Reproducibility, Sensitivity and Specificity

An ideal lyophilization formulation, for example, should stabilize an enzyme in a freeze-dried format and allow very fast rehydration and reactivation of the enzyme preparations without impacting its performance post rehydration. An ideal formulation should stabilize an enzyme in a freeze-dried or air-dried format and allow fast rehydration and reactivation of the enzyme preparations without impacting its performance post rehydration.

Meridian offers general and sample specific master mixes and glycerol-free enzymes and buffers for the preparation of both lyophilization and air-drying of your assays.

Advanced Enzyme Solutions for Molecular Biology Applications

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Why We Are Second To None

Meridian offers diagnostic manufacturers the complete solution with over 3,000 antigens and antibodies covering more than 500 diseases and an extensive range of specialty qPCR/RT-qPCR master mixes and molecular enzymes all manufactured under ISO13485 regulations.

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